6.2.1.1Gene ontology ID
GO:0003987
Definition
Catalysis of the reaction: ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA
Synonyms
1. acetate thiokinase activity
2. acetate to acetyl-CoA
3. acetate:CoA ligase (AMP-forming)
4. acetic thiokinase activity
5. acetyl activating enzyme
6. acetyl CoA ligase activity
7. acetyl CoA synthase activity
8. acetyl coenzyme A synthetase activity
9. acetyl-activating enzyme activity
10. acetyl-CoA synthase activity
11. acetyl-CoA synthetase activity
12. acetyl-coenzyme A synthase activity
13. ACS
14. acyl-activating enzyme activity
15. short chain fatty acyl-CoA synthetase activity
16. short-chain acyl-coenzyme A synthetase activity
References
1. EC 6.2.1.12. MetaCyc ACETATE--COA-LIGASE-RXN3. Reactome: R-HSA-449911 "acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial]"
4. Reactome: R-HSA-71735 "acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic]"
5. Reactome: R-HSA-8875071 "ACSS3 ligates CoA to CH3COO-"
6. RHEA: 23176
Legend
is an element of the parent element
is a part of the parent element
is related to the parent element
derives from the parent element
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at least 1 tissue/ enzyme/ localization link in this branch
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tissue/ enzyme/ localization link to BRENDA