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Gene ontology
Version 2014-12-22
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Details for sphingomyelin synthase activity
2.7.8.27
Gene ontology ID
GO:0033188
Definition
Catalysis of the reaction: 1,2-diacyl-sn-glycero-3-phosphocholine + ceramide = 1,2-diacyl-sn-glycerol + sphingomyelin
Synonyms
1. ceramide:phosphatidylcholine cholinephosphotransferase activity
2. phosphatidylcholine:ceramide cholinephosphotransferase activity
3. SM synthase activity
4. SMS1
5. SMS2
References
1. EC 2.7.8.27
2. RHEA: 18765
3. KEGG REACTION: R08969
4. MetaCyc 2.7.8.27-RXN
5. Reactome: R-HSA-429786 "phosphatidylcholine + ceramide <=> sphingomyelin + diacylglycerol [SGMS2]"
6. Reactome: R-HSA-429798 "phosphatidylcholine + ceramide <=> sphingomyelin + diacylglycerol [SGMS1]"
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