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Gene ontology
Version 2014-12-22
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Details for thymidylate synthase activity
2.1.1.45
Gene ontology ID
GO:0004799
Definition
Catalysis of the reaction: 5,10-methylenetetrahydrofolate + dUMP = 7,8-dihydrofolate + thymidylate
Synonyms
1. 5,10-methylenetetrahydrofolate:dUMP C-methyltransferase activity
2. dTMP synthase activity
3. methylenetetrahydrofolate:dUMP C-methyltransferase activity
4. thymidylate synthetase activity
5. TMP synthetase activity
References
1. EC 2.1.1.45
2. RHEA: 12104
3. KEGG REACTION: R02101
4. MetaCyc THYMIDYLATESYN-RXN
5. Reactome: R-HSA-73605 "dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate"
Legend
is an element of the parent element
is a part of the parent element
is related to the parent element
derives from the parent element
// at least 1 tissue/ enzyme/ localization link in this branch
// tissue/ enzyme/ localization link to BRENDA
Condensed Tree View
Gene ontology
molecular_function is a
catalytic activity is a
transferase activity is a
transferase activity, transferring one-carbon groups is a
methyltransferase activity is a
5,10-methylenetetrahydrofolate-dependent methyltransferase activity is a
thymidylate synthase activity is a
Tree view
Gene ontology
biological_process is a
cellular_component is a
molecular_function is a
binding is a
catalytic activity is a
catalytic activity, acting on a protein is a
catalytic activity, acting on DNA is a
catalytic activity, acting on RNA is a
cyclase activity is a
hydrolase activity is a
isomerase activity is a
ligase activity is a
lyase activity is a
peptidoglycan muralytic activity is a
transferase activity is a
Atg8 ligase activity is a
CDP-alcohol phosphotransferase activity is a
glucanosyltransferase activity is a
Kdo transferase activity is a
mannosylphosphate transferase activity is a
molybdopterin molybdotransferase activity is a
transferase activity, transferring acyl groups is a
transferase activity, transferring aldehyde or ketonic groups is a
transferase activity, transferring alkyl or aryl (other than methyl) groups is a
transferase activity, transferring glycosyl groups is a
transferase activity, transferring nitrogenous groups is a
transferase activity, transferring one-carbon groups is a
carboxyl- or carbamoyltransferase activity is a
hydroxymethyl-, formyl- and related transferase activity is a
methyltransferase activity is a
(R)-reticuline 7-O-methyltransferase activity is a
(S)-reticuline 7-O-methyltransferase activity is a
1-hydroxy-6-methoxypyrene methyltransferase activity is a
1-hydroxypyrene methyltransferase activity is a
1-phenanthrol methyltransferase activity is a
12-demethyl-elloramycin C12a O-methyltransferase activity is a
2,7,4'-trihydroxyisoflavanone-4'-O-methyltransferase activity is a
2-methyl-6-geranylgeranyl-1,4-benzoquinol methyltransferase activity is a
2-polyprenyl-6-hydroxyphenol methylase activity is a
3',4',5'-trimethylmyricetin 3-O-methyltransferase activity is a
3',4',5'-trimethylmyricetin 7-O-methyltransferase activity is a
3'-O-methyltricetin O methyl transferase activity is a
3,5-dihydroxyanisole O-methyltransferase activity is a
3,5-dimethoxyphenol O-methyltransferase activity is a
3-aminomethylindole N-methyltransferase activity is a
3-methoxy-5-hydroxytoluene O-methyltransferase activity is a
3-methylquercetin 3'-O-methyltransferase activity is a
4,5-dihydroxybenzo(a)pyrene methyltransferase activity is a
4-hydroxytryptamine 4-phosphate methyltransferase activity is a
5,10-methylenetetrahydrofolate-dependent methyltransferase activity is a
thymidylate synthase (FAD) activity is a
thymidylate synthase activity is a
5-methyl-5,6,7,8-tetrahydromethanopterin-dependent methyltransferase activity is a
5-methyl-phenazine-1-carboxylate N-methyltransferase activity is a
5-methyltetrahydrofolate-dependent methyltransferase activity is a
5-methyltetrahydropteroyltri-L-glutamate-dependent methyltransferase activity is a
5-n-alk(en)ylresorcinol O-methyltransferase activity is a
6a-hydroxymaackiain-3-O-methyltransferase activity is a
7,8,4'-trihydroxyflavone methyltransferase activity is a
7-methylmyricetin 4'-O-methyltransferase activity is a
8-demethylnovobiocic acid C8-methyltransferase activity is a
adrenaline O-methyltransferase activity is a
aminomethyltransferase activity is a
apigenin 7-O-methyltransferase activity is a
bixin methyltransferase activity is a
C-methyltransferase activity is a
C4-demethylase activity is a
C4-methyltransferase activity is a
caffeoylglucose 3-O-methyltransferase activity is a
cirsimaritin 4'-O-methyltransferase activity is a
cobalt-factor II C20-methyltransferase activity is a
cobalt-precorrin-3 C17-methyltransferase activity is a
cobalt-precorrin-5B C1-methyltransferase activity is a
cobalt-precorrin-6B C5-methyltransferase activity is a
cobalt-precorrin-7 C15-methyltransferase activity is a
corydaline synthase activity is a
daphnetin-8-O-methyltransferase activity is a
demethylmenaquinone methyltransferase activity is a
demethylrebeccamycin--D-glucose O-methyltransferase activity is a
dimethyl selenide methyltransferase activity is a
dimethylamine methyltransferase activity is a
dimethylarsinite methyltransferase activity is a
dTDP-3-amino-4-oxo-2,3,6-trideoxy-alpha-D-glucose N,N-dimethyltransferase activity is a
dTDP-3-amino-4-oxo-2,3,6-trideoxy-alpha-D-glucose N-methyltransferase activity is a
dTDP-3-N-methylamino-4-oxo-2,3,6-trideoxy-alpha-D-glucose N-methyltransferase activity is a
eriodictyol 3'-O-methyltransferase activity is a
eriodictyol 4'-O-methyltransferase activity is a
erythromycin C 3''-o-methyltransferase activity is a
erythromycin D 3''-o-methyltransferase activity is a
flavanone 4'-O-methyltransferase activity is a
genkwanin 4'-O-methyltransferase activity is a
gibberellin A20 carboxyl methyltransferase activity is a
gibberellin A34 carboxyl methyltransferase activity is a
gibberellin A4 carboxyl methyltransferase activity is a
gibberellin A9 carboxyl methyltransferase activity is a
gossypetin 8-methyl ester 3'-O-methyltransferase activity is a
hydrogen selenide methyltransferase activity is a
hydroxyneurosporene-O-methyltransferase activity is a
indole acetic acid carboxyl methyltransferase activity is a
indole-3-acetate carboxyl methyltransferase activity is a
isorhamnetin 3-O-methyltransferase activity is a
isoscopoletin-O-methyltransferase activity is a
juvenile hormone acid methyltransferase activity is a
kaempferide 3-O-methyltransferase activity is a
kaempferide 7-O-methyltransferase activity is a
kaempferol 3-O-methyltransferase activity is a
L-dopa O-methyltransferase activity is a
ladanein 6-O-methyltransferase activity is a
laricitrin 4'-O-methyltransferase activity is a
malonyl-CoA methyltransferase activity is a
methaneselenol methyltransferase activity is a
methanol-5-hydroxybenzimidazolylcobamide Co-methyltransferase activity is a
methanol-specific methylcobalamin:coenzyme M methyltransferase activity is a
methyl jasmonate methylesterase activity is a
methylamine-specific methylcobalamin:coenzyme M methyltransferase activity is a
methylenetetrahydrofolate-tRNA-(uracil-5-)-methyltransferase (FADH2-oxidizing) activity is a
methyltetrahydrofolate:corrinoid/iron-sulfur protein methyltransferase activity is a
methylthiol:coenzyme M methyltransferase activity is a
monomethylamine methyltransferase activity is a
mycinamicin VI 2''-O-methyltransferase activity is a
myricetin 7-O-methyltransferase activity is a
N-methyl-3-aminomethylindole N-methyltransferase activity is a
N-methyltransferase activity is a
naringenin 7-O-methyltransferase activity is a
norbixin methyltransferase activity is a
O-methyltransferase activity is a
orcinol O-methyltransferase activity is a
P-methyltransferase activity is a
paraxanthine:S-adenosyl-L-methionine 3-N-methyltransferase activity is a
patuletin 3'-O-methyltransferase activity is a
phloroglucinol O-methyltransferase activity is a
precorrin-6A synthase (deacetylating) activity is a
protein-(glutamine-N5) methyltransferase activity is a
quercetin 3'-O-methyltransferase activity is a
quercetin 7-O-methyltransferase activity is a
resveratrol 3,5-O-dimethyltransferase activity is a
rhamnetin 3'-O-methyltransferase activity is a
rhamnetin 3-O-methyltransferase activity is a
rhamnetin 4'-O-methyltransferase activity is a
S-adenosyl-L-methionine:(S)-corytuberine-N-methyltransferase activity is a
S-adenosyl-L-methionine:eugenol-O-methyltransferase activity is a
S-adenosylmethionine-dependent methyltransferase activity is a
S-adenosylmethionine:2-demethylmenaquinol methyltransferase activity is a
S-adenosylmethionine:2-demethylmenaquinol-7 methyltransferase activity is a
S-adenosylmethionine:2-demethylquinol-8 methyltransferase activity is a
S-methyltransferase activity is a
scutellarein 7-methyl ether 4'-O-methyltransferase activity is a
scutellarein 7-methyl ether 6-O-methyltransferase activity is a
Se-methyltransferase activity is a
selenol Se-methyltransferase activity is a
sterol 24C methyltransferase activity is a
syringetin 3-O-methyltransferase activity is a
syringetin 7-O-methyltransferase activity is a
tetracenomycin B3 8-O-methyl transferase activity is a
theobromine:S-adenosyl-L-methionine 1-N-methyltransferase activity is a
thiocyanate methyltransferase activity is a
TRIBOA-glucoside methyltransferase activity is a
tricaffeoyl spermidine O-methyltransferase activity is a
tricetin O-methytransferase activity is a
trimethylamine methyltransferase activity is a
[methyl-Co(III) methanol-specific corrinoid protein]:coenzyme M methyltransferase activity is a
transferase activity, transferring phosphorus-containing groups is a
transferase activity, transferring selenium-containing groups is a
transferase activity, transferring sulfur-containing groups is a
UDP-L-rhamnose synthase activity is a
molecular transducer activity is a
nutrient reservoir activity is a
protein tag is a
small molecule sensor activity is a
structural molecule activity is a
transcription regulator activity is a
transporter activity is a