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Gene ontology
Version 2014-12-22
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Details for glutathione synthase activity
6.3.2.3
Gene ontology ID
GO:0004363
Definition
Catalysis of the reaction: L-gamma-glutamyl-L-cysteine + ATP + glycine = ADP + glutathione + 2 H(+) + phosphate
Synonyms
1. gamma-L-glutamyl-L-cysteine:glycine ligase (ADP-forming)
2. glutathione synthetase activity
3. GSH synthetase activity
References
1. EC 6.3.2.3
2. RHEA: 13557
3. KEGG REACTION: R00497
4. MetaCyc GLUTATHIONE-SYN-RXN
5. Reactome: R-HSA-174394 "GSS:Mg2+ dimer synthesizes GSH"
6. Reactome: R-HSA-5602901 "Defective GSS does not synthesize GSH"
Legend
is an element of the parent element
is a part of the parent element
is related to the parent element
derives from the parent element
// at least 1 tissue/ enzyme/ localization link in this branch
// tissue/ enzyme/ localization link to BRENDA
Condensed Tree View
Gene ontology
biological_process is a
cellular process is a
cellular metabolic process is a
cellular biosynthetic process is a
cellular nitrogen compound biosynthetic process is a
amide biosynthetic process is a
peptide biosynthetic process is a
nonribosomal peptide biosynthetic process is a
glutathione biosynthetic process is a
glutathione synthase activity part of
Tree view
Gene ontology
biological_process is a
behavior is a
biological adhesion is a
biological phase is a
biological regulation is a
biomineralization is a
carbohydrate utilization is a
carbon utilization is a
cellular process is a
actin filament-based process is a
cell activation is a
cell adhesion molecule production is a
cell aggregation is a
cell communication is a
cell cycle is a
cell death is a
cell division is a
cell growth is a
cell killing is a
cell population proliferation is a
cell recognition is a
cell wall organization or biogenesis is a
cell-cell fusion is a
cellular component organization or biogenesis is a
cellular detoxification is a
cellular developmental process is a
cellular localization is a
cellular metabolic process is a
bioluminescence is a
cellular alcohol metabolic process is a
cellular aldehyde metabolic process is a
cellular alkane metabolic process is a
cellular alkene metabolic process is a
cellular alkyne metabolic process is a
cellular aromatic compound metabolic process is a
cellular biosynthetic process is a
antibiotic biosynthetic process is a
cellular carbohydrate biosynthetic process is a
cellular macromolecule biosynthetic process is a
cellular nitrogen compound biosynthetic process is a
alkaloid biosynthetic process is a
amide biosynthetic process is a
allantoin biosynthetic process is a
ansamycin biosynthetic process is a
asparagine biosynthetic process is a
biotin biosynthetic process is a
cellular lactam biosynthetic process is a
ceramide biosynthetic process is a
dethiobiotin biosynthetic process is a
fatty acid primary amide biosynthetic process is a
formamide biosynthetic process is a
ochratoxin A biosynthetic process is a
pantothenate biosynthetic process is a
peptide biosynthetic process is a
antimicrobial peptide biosynthetic process is a
bradykinin biosynthetic process is a
carnosine biosynthetic process is a
depsipeptide biosynthetic process is a
gramicidin S biosynthetic process is a
leukotriene D4 biosynthetic process is a
nonribosomal peptide biosynthetic process is a
amino acid activation for nonribosomal peptide biosynthetic process part of
amino acid ligation activity by nonribosomal peptide synthase part of
glutathione biosynthetic process is a
glutathione synthase activity part of
peptidyl carrier protein activity part of
siderophore biosynthetic process is a
phytochelatin biosynthetic process is a
pseurotin A biosynthetic process is a
pyrrolysine biosynthetic process is a
spermidine hydroxycinnamate conjugate biosynthetic process is a
sphingomyelin biosynthetic process is a
tensidol A biosynthetic process is a
tensidol B biosynthetic process is a
urea cycle is a
ureide biosynthetic process is a
amine biosynthetic process is a
amino-acid betaine biosynthetic process is a
carbamoyl phosphate biosynthetic process is a
cyanate biosynthetic process is a
cyanide biosynthetic process is a
dipyrrin biosynthetic process is a
flavin-containing compound biosynthetic process is a
nitrile biosynthetic process is a
phytosphingosine biosynthetic process is a
pyridine-containing compound biosynthetic process is a
pyrimidine-containing compound biosynthetic process is a
pyrroloquinoline quinone biosynthetic process is a
sphinganine biosynthetic process is a
sphingosine biosynthetic process is a
cofactor biosynthetic process is a
glycerol ether biosynthetic process is a
glycerolipid biosynthetic process is a
heterocycle biosynthetic process is a
isoprenoid biosynthetic process is a
ketone biosynthetic process is a
ketone body biosynthetic process is a
membrane lipid biosynthetic process is a
mucilage biosynthetic process is a
neutral lipid biosynthetic process is a
organic acid biosynthetic process is a
organic phosphonate biosynthetic process is a
organomercury biosynthetic process is a
peptidyl-dehydroalanine biosynthetic process from peptidyl-tyrosine or peptidyl-serine is a
peptidyl-diphthine biosynthetic process from peptidyl-histidine is a
peptidyl-thyronine biosynthetic process from peptidyl-tyrosine is a
phospholipid biosynthetic process is a
polyphosphate biosynthetic process is a
rhodopsin biosynthetic process is a
sulfur compound biosynthetic process is a
toxin biosynthetic process is a
vitamin biosynthetic process is a
cellular carbohydrate metabolic process is a
cellular catabolic process is a
cellular ketone body metabolic process is a
cellular ketone metabolic process is a
cellular lipid metabolic process is a
cellular macromolecule metabolic process is a
cellular metabolic compound salvage is a
cellular modified amino acid metabolic process is a
cellular nitrogen compound metabolic process is a
cellular organohalogen metabolic process is a
chemosynthesis is a
cofactor metabolic process is a
drug metabolic process is a
generation of precursor metabolites and energy is a
heterocycle metabolic process is a
hydroperoxide metabolic process is a
metabolite repair is a
mucilage metabolic process is a
one-carbon metabolic process is a
organic acid metabolic process is a
organometal metabolic process is a
phosphorus metabolic process is a
photosynthesis is a
prenylation is a
reactive oxygen species metabolic process is a
selenium compound metabolic process is a
sulfur compound metabolic process is a
toxin metabolic process is a
xenobiotic metabolic process is a
cellular pigmentation is a
cellular process involved in reproduction in multicellular organism is a
cellular response to stimulus is a
chromosome segregation is a
cytolysis is a
DNA clamp unloading is a
ensheathment of neurons is a
establishment or maintenance of cell polarity is a
establishment or maintenance of cell type involved in phenotypic switching is a
export from cell is a
intercellular transport is a
intermediate filament-based process is a
light absorption is a
localization of cell is a
membrane docking is a
microtubule organizing center localization is a
microtubule-based process is a
movement of cell or subcellular component is a
multi-organism cellular process is a
phenotypic switching is a
plasmid maintenance is a
process utilizing autophagic mechanism is a
protein folding is a
protein unfolding is a
RNA folding is a
signaling receptor ligand precursor processing is a
stomatal movement is a
syncytium formation is a
transmembrane transport is a
transposition is a
vacuolar transport is a
vesicle-mediated transport is a
detoxification is a
developmental process is a
growth is a
immune system process is a
interspecies interaction between organisms is a
intraspecies interaction between organisms is a
localization is a
locomotion is a
metabolic process is a
multi-organism process is a
multicellular organismal process is a
pigmentation is a
reproduction is a
response to stimulus is a
rhythmic process is a
signaling is a
cellular_component is a
molecular_function is a
binding is a
catalytic activity is a
catalytic activity, acting on a protein is a
catalytic activity, acting on DNA is a
catalytic activity, acting on RNA is a
cyclase activity is a
hydrolase activity is a
isomerase activity is a
ligase activity is a
beta-alanyl-dopamine synthase activity is a
delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase activity is a
ligase activity, forming carbon-carbon bonds is a
ligase activity, forming carbon-nitrogen bonds is a
(-)-jasmonoyl-isoleucine synthetase activity is a
5-(carboxyamino)imidazole ribonucleotide synthase activity is a
acid-amino acid ligase activity is a
2,3-dihydroxybenzoate-serine ligase activity is a
4-aminobenzoate amino acid synthetase activity is a
4-hydroxybenzoate amino acid synthetase activity is a
aerobactin synthase activity is a
aliphatic aldoxime dehydratase activity is a
benzoate amino acid synthetase activity is a
carnitine-CoA ligase activity is a
carnosine synthase activity is a
coenzyme F420-0 gamma-glutamyl ligase activity is a
coenzyme F420-0:L-glutamate ligase activity is a
coenzyme F420-1:gamma-L-glutamate ligase activity is a
coenzyme F420-2 alpha-glutamyl ligase activity is a
cyanophycin synthetase activity is a
cyclo-acetoacetyl-L-tryptophan synthetase activity is a
D-alanine-alanyl-poly(glycerolphosphate) ligase activity is a
D-alanine-D-alanine ligase activity is a
gamma-glutamylhistamine synthase activity is a
glutamate-cysteine ligase activity is a
homocarnosine synthase activity is a
homoglutathione synthase activity is a
indole-3-acetic acid amido synthetase activity is a
jasmonate-amino synthetase activity is a
L-amino-acid alpha-ligase activity is a
L-propargylglycine--L-glutamate ligase activity is a
N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase activity is a
pantoate-beta-alanine ligase activity is a
phenylacetaldoxime dehydratase activity is a
phosphopantothenate--cysteine ligase activity is a
phosphoribosylaminoimidazolesuccinocarboxamide synthase activity is a
tyrosine-arginine ligase activity is a
UDP-N-acetylmuramate-L-alanine ligase activity is a
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--D-lysine ligase activity is a
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-L-lysine ligase activity is a
UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity is a
UDP-N-acetylmuramoylalanine-D-glutamate ligase activity is a
UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase activity is a
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity is a
vanillate amino acid synthetase activity is a
acid-ammonia (or amide) ligase activity is a
adenylosuccinate synthase activity is a
argininosuccinate synthase activity is a
biotin carboxylase activity is a
carbamoyl-phosphate synthase (ammonia) activity is a
carbon-nitrogen ligase activity, with glutamine as amido-N-donor is a
citrate-L-glutamate ligase activity is a
CTP synthase activity is a
cyclo-ligase activity is a
formate-dihydrofolate ligase activity is a
formate-tetrahydrofolate ligase activity is a
glutamate-methylamine ligase activity is a
imidazoleacetate-phosphoribosyldiphosphate ligase activity is a
indole-3-acetyl-glutamate synthetase activity is a
indole-3-acetyl-glycine synthetase activity is a
indole-3-acetyl-isoleucine synthetase activity is a
indole-3-acetyl-leucine synthetase activity is a
indole-3-acetyl-methionine synthetase activity is a
indole-3-acetyl-phenylalanine synthetase activity is a
indole-3-acetyl-proline synthetase activity is a
indole-3-acetyl-tryptophan synthetase activity is a
indole-3-acetyl-tyrosine synthetase activity is a
indole-3-acetyl-valine synthetase activity is a
jasmonoyl-leucine synthetase activity is a
jasmonoyl-valine synthetase activity is a
N-(4-aminobenzoyl)-L-glutamate synthetase activity is a
N-(4-hydroxybenzoyl)-L-glutamate synthetase activity is a
N-acetyl-L-aspartate-L-glutamate ligase activity is a
N-benzoyl-L-glutamate synthetase activity is a
N-vanillate-L-glutamate synthetase activity is a
nicotinate phosphoribosyltransferase activity is a
phosphoribosylamine-glycine ligase activity is a
ribose-5-phosphate-ammonia ligase activity is a
sulfinylpropanyl adenylate synthase is a
urea carboxylase activity is a
ligase activity, forming carbon-oxygen bonds is a
ligase activity, forming carbon-sulfur bonds is a
ligase activity, forming nitrogen-metal bonds is a
ligase activity, forming phosphoric ester bonds is a
O antigen ligase activity is a
tRNA-specific 2-thiouridylase activity is a
lyase activity is a
peptidoglycan muralytic activity is a
transferase activity is a
molecular transducer activity is a
nutrient reservoir activity is a
protein tag is a
small molecule sensor activity is a
structural molecule activity is a
transcription regulator activity is a
transporter activity is a