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Gene ontology
Version 2014-12-22
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Details for thioredoxin-disulfide reductase activity
1.8.1.9
Gene ontology ID
GO:0004791
Definition
Catalysis of the reaction: NADP(+) + thioredoxin = H(+) + NADPH + thioredoxin disulfide
Synonyms
1. NADP--thioredoxin reductase activity
2. NADPH--thioredoxin reductase activity
3. NADPH2:oxidized thioredoxin oxidoreductase activity
4. NADPH:oxidized thioredoxin oxidoreductase activity
5. thioredoxin disulfide reductase activity
6. thioredoxin reductase (NADPH) activity
7. thioredoxin-disulphide reductase activity
8. thioredoxin:NADP+ oxidoreductase activity
References
1. EC 1.8.1.9
2. RHEA: 20345
3. KEGG REACTION: R02016
4. MetaCyc THIOREDOXIN-REDUCT-NADPH-RXN
5. Reactome: R-HSA-1222485 "TrxB reactivates TrxA"
6. Reactome: R-HSA-3323050 "TXNRD2 catalyzes the reduction of TXN2 by NADPH"
7. Reactome: R-HSA-73646 "thioredoxin, oxidized + NADPH + H+ => thioredoxin, reduced + NADP+"
8. Reactome: R-HSA-9617735 "TXN disrupts FOXO4 complex with EP300"
Legend
is an element of the parent element
is a part of the parent element
is related to the parent element
derives from the parent element
// at least 1 tissue/ enzyme/ localization link in this branch
// tissue/ enzyme/ localization link to BRENDA
Condensed Tree View
Gene ontology
biological_process is a
cellular process is a
cellular detoxification is a
cellular oxidant detoxification is a
antioxidant activity part of
thioredoxin-disulfide reductase activity is a
Tree view
Gene ontology
biological_process is a
behavior is a
biological adhesion is a
biological phase is a
biological regulation is a
biomineralization is a
carbohydrate utilization is a
carbon utilization is a
cellular process is a
actin filament-based process is a
cell activation is a
cell adhesion molecule production is a
cell aggregation is a
cell communication is a
cell cycle is a
cell death is a
cell division is a
cell growth is a
cell killing is a
cell population proliferation is a
cell recognition is a
cell wall organization or biogenesis is a
cell-cell fusion is a
cellular component organization or biogenesis is a
cellular detoxification is a
cellular detoxification of aldehyde is a
cellular detoxification of cadmium ion is a
cellular detoxification of copper ion is a
cellular detoxification of fluoride is a
cellular detoxification of nitrogen compound is a
cellular oxidant detoxification is a
antioxidant activity part of
glutathione dehydrogenase (ascorbate) activity is a
glutathione-disulfide reductase activity is a
peroxidase activity is a
peroxiredoxin activity is a
sulfiredoxin activity is a
superoxide dismutase activity is a
superoxide reductase activity is a
thioredoxin-disulfide reductase activity is a
cellular detoxification of hydrogen peroxide is a
removal of superoxide radicals is a
toxic metabolite repair is a
cellular developmental process is a
cellular localization is a
cellular metabolic process is a
cellular pigmentation is a
cellular process involved in reproduction in multicellular organism is a
cellular response to stimulus is a
chromosome segregation is a
cytolysis is a
DNA clamp unloading is a
ensheathment of neurons is a
establishment or maintenance of cell polarity is a
establishment or maintenance of cell type involved in phenotypic switching is a
export from cell is a
intercellular transport is a
intermediate filament-based process is a
light absorption is a
localization of cell is a
membrane docking is a
microtubule organizing center localization is a
microtubule-based process is a
movement of cell or subcellular component is a
multi-organism cellular process is a
phenotypic switching is a
plasmid maintenance is a
process utilizing autophagic mechanism is a
protein folding is a
protein unfolding is a
RNA folding is a
signaling receptor ligand precursor processing is a
stomatal movement is a
syncytium formation is a
transmembrane transport is a
transposition is a
vacuolar transport is a
vesicle-mediated transport is a
detoxification is a
developmental process is a
growth is a
immune system process is a
interspecies interaction between organisms is a
intraspecies interaction between organisms is a
localization is a
locomotion is a
metabolic process is a
adaptive thermogenesis is a
ATP metabolic process is a
biosynthetic process is a
catabolic process is a
collagen metabolic process is a
demethylation is a
glycosylation is a
hydrogen metabolic process is a
methylation is a
multi-organism metabolic process is a
NAD metabolic process is a
NADH metabolic process is a
NADP metabolic process is a
nitrogen compound metabolic process is a
organic substance metabolic process is a
oxidation-reduction process is a
iodide oxidation is a
oxidative deethylation is a
oxidoreductase activity part of
1,1,1-trichloroethane reductive dehalogenase activity is a
1,1,2-trichloroethene reductive dehalogenase activity is a
1,1-dichloro-2,2-bis(4-chlorophenyl)ethene dehalogenase activity is a
1,1-dichloroethane reductive dehalogenase activity is a
1,2-dichloroethene reductive dehalogenase activity is a
2,4-dichloroaniline reductive dehalogenase activity is a
2,4-dichlorophenoxyacetate dehalogenase activity is a
2,5-dichlorohydroquinone reductive dehalogenase activity is a
2-chloro-N-isopropylacetanilide reductive dehalogenase activity is a
2-octaprenylphenol hydroxylase activity is a
2-octoprenyl-3-methyl-6-methoxy-1,4-benzoquinone hydroxylase activity is a
3,3',5,5'-tetrabromobisphenol A reductive dehalogenase activity is a
3,3',5-tribromobisphenol A reductive dehalogenase activity is a
3,3'-dibromobisphenol A reductive dehalogenase activity is a
3,8-divinyl protochlorophyllide a 8-vinyl reductase activity is a
3-monobromobisphenol A reductive dehalogenase activity is a
alpha-ketoacid dehydrogenase activity is a
arsenate reductase activity is a
chlorate reductase activity is a
chromate reductase activity is a
crotonyl-CoA reductase activity is a
delta1-piperideine-6-carboxylate dehydrogenase activity is a
dihydronicotinamide riboside quinone reductase activity is a
dihydropterin oxidase activity is a
dimethylarsinate reductase activity is a
dioxygenase activity is a
epoxyqueuosine reductase activity is a
fatty acid alpha-hydroxylase activity is a
geranylgeranyl reductase activity is a
glycyl-radical enzyme activating activity is a
heme-copper terminal oxidase activity is a
hydroxymethylbutenyl pyrophosphate reductase activity is a
malolactic enzyme activity is a
monooxygenase activity is a
NADPH-adrenodoxin reductase activity is a
NADPH:sulfur oxidoreductase activity is a
ortho-trichlorophenol reductive dehalogenase activity is a
oxidoreductase activity, acting on a heme group of donors is a
oxidoreductase activity, acting on a sulfur group of donors is a
adenylyl-sulfate reductase activity is a
CoB--CoM heterodisulfide reductase activity is a
dimethyl sulfoxide reductase activity is a
disulfide oxidoreductase activity is a
hydrogensulfite reductase activity is a
oxidoreductase activity, acting on a sulfur group of donors, cytochrome as acceptor is a
oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor is a
oxidoreductase activity, acting on a sulfur group of donors, iron-sulfur protein as acceptor is a
oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor is a
2-oxopropyl-CoM reductase (carboxylating) activity is a
alkyl hydroperoxide reductase activity is a
alkylhydroperoxide reductase activity is a
asparagusate reductase activity is a
bis-gamma-glutamylcystine reductase activity is a
CoA-glutathione reductase activity is a
cystine reductase activity is a
dihydrolipoyl dehydrogenase activity is a
hypotaurine dehydrogenase activity is a
mycothione reductase activity is a
sulfite reductase (NADPH) activity is a
oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor is a
oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor is a
reduced coenzyme F420:heterodisulfide oxidoreductase activity is a
sulfite reductase (coenzyme F420) activity is a
sulfite reductase activity is a
sulfur:ferric ion oxidoreductase activity is a
tetrachloro-p-hydroquinone reductive dehalogenase activity is a
trichloro-p-hydroquinone reductive dehalogenase activity is a
oxidoreductase activity, acting on CH or CH2 groups is a
oxidoreductase activity, acting on CH-OH group of donors is a
oxidoreductase activity, acting on diphenols and related substances as donors is a
oxidoreductase activity, acting on halogen in donors is a
oxidoreductase activity, acting on hydrogen as donor is a
oxidoreductase activity, acting on iron-sulfur proteins as donors is a
oxidoreductase activity, acting on NAD(P)H is a
oxidoreductase activity, acting on other nitrogenous compounds as donors is a
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen is a
oxidoreductase activity, acting on peroxide as acceptor is a
oxidoreductase activity, acting on phosphorus or arsenic in donors is a
oxidoreductase activity, acting on reduced flavodoxin as donor is a
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen is a
oxidoreductase activity, acting on superoxide radicals as acceptor is a
oxidoreductase activity, acting on the aldehyde or oxo group of donors is a
oxidoreductase activity, acting on the CH-CH group of donors is a
oxidoreductase activity, acting on the CH-NH group of donors is a
oxidoreductase activity, acting on the CH-NH2 group of donors is a
oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond is a
oxidoreductase activity, oxidizing metal ions is a
oxygen evolving activity is a
perchlorate reductase activity is a
phthalate dioxygenase reductase activity is a
pyrogallol hydroxytransferase activity is a
reduced coenzyme F420 dehydrogenase activity is a
reduced coenzyme F420 oxidase activity is a
reduced coenzyme F420:quinone oxidoreductase activity is a
selenate reductase activity is a
sphingosine hydroxylase activity is a
steroid dehydrogenase activity is a
sulfur oxygenase reductase activity is a
sulfur reductase activity is a
tetrachloroethene reductive dehalogenase activity is a
tetrahydrothiophene 1-oxide reductase activity is a
thyroxine 5'-deiodinase activity is a
thyroxine 5-deiodinase activity is a
trimethylarsine oxidase activity is a
tyramine-beta hydroxylase activity is a
uracil oxygenase activity is a
vinyl chloride reductive dehalogenase activity is a
violaxanthin de-epoxidase activity is a
thioredoxin reduction is a
pigment metabolic process is a
primary metabolic process is a
respiratory burst is a
secondary metabolic process is a
small molecule metabolic process is a
tartrate metabolic process is a
tyrocidine metabolic process is a
multi-organism process is a
multicellular organismal process is a
pigmentation is a
reproduction is a
response to stimulus is a
rhythmic process is a
signaling is a
cellular_component is a
molecular_function is a