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Gene ontology
Version 2014-12-22
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Details for hepoxilin A3 synthase activity
Gene ontology ID
GO:0051120
Definition
Catalysis of the reaction: 12S-5Z,8Z,10E,14Z-12-hydro(pero)xy-eicosa-5,8,10,14-tetraenoic acid = (5Z,9E,14Z)-(8,11R,12S)-11,12-epoxy-8-hydroxyicosa-5,9,14-trienoate. 12S-5Z,8Z,10E,14Z-12-hydro(pero)xy-eicosa-5,8,10,14-tetraenoic acid is also known as 12S-HpETE, and (5Z,9E,14Z)-(8,11R,12S)-11,12-epoxy-8-hydroxyicosa-5,9,14-trienoate as hepoxilin A3
References
1. PMID 15123652
2. Reactome: R-HSA-2161794 "Arachidonic acid is converted to HXA3/B3 by ALOX12"
3. Reactome: R-HSA-8942208 "ALOXE3 isomerises 12R-HpETE to HXA3"
Legend
is an element of the parent element
is a part of the parent element
is related to the parent element
derives from the parent element
// at least 1 tissue/ enzyme/ localization link in this branch
// tissue/ enzyme/ localization link to BRENDA
Condensed Tree View
Gene ontology
molecular_function is a
CENP-A containing nucleosome binding is a
catalytic activity is a
tRNA-5-taurinomethyluridine 2-sulfurtransferase is a
isomerase activity is a
hepoxilin A3 synthase activity is a
UDP-glucosamine 4-epimerase activity is a
citrate-CoA ligase activity is a
succinate-CoA ligase (ADP-forming) activity is a
Tree view
Gene ontology
biological_process is a
cellular_component is a
molecular_function is a
binding is a
catalytic activity is a
catalytic activity, acting on a protein is a
catalytic activity, acting on DNA is a
catalytic activity, acting on RNA is a
cyclase activity is a
hydrolase activity is a
isomerase activity is a
(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity is a
4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase activity is a
cis-trans isomerase activity is a
dihydroneopterin triphosphate 2'-epimerase activity is a
eoxin A4 synthase activity is a
hepoxilin A3 synthase activity is a
hexulose-6-phosphate isomerase activity is a
intramolecular lyase activity is a
intramolecular oxidoreductase activity is a
intramolecular transferase activity is a
N-acylmannosamine-6-phosphate 2-epimerase activity is a
peroxynitrite isomerase activity is a
racemase and epimerase activity is a
16-hydroxysteroid epimerase activity is a
allantoin racemase activity is a
alpha-methylacyl-CoA racemase activity is a
hydantoin racemase activity is a
methylmalonyl-CoA epimerase activity is a
NADHX epimerase activity is a
NADPHX epimerase activity is a
racemase and epimerase activity, acting on amino acids and derivatives is a
racemase and epimerase activity, acting on carbohydrates and derivatives is a
ADP-glyceromanno-heptose 6-epimerase activity is a
aldose 1-epimerase activity is a
allulose 6-phosphate 3-epimerase activity is a
CDP-abequose epimerase activity is a
cellobiose epimerase activity is a
chondroitin-glucuronate 5-epimerase activity is a
D-galactose 6-phosphate 1-epimerase activity is a
D-mannose 6-phosphate 1-epimerase activity is a
dTDP-4-dehydrorhamnose 3,5-epimerase activity is a
GDP-mannose 3,5-epimerase activity is a
glucose-6-phosphate 1-epimerase activity is a
heparosan-N-sulfate-glucuronate 5-epimerase activity is a
L-fucose mutarotase activity is a
L-rhamnose mutarotase activity is a
L-ribulose-5-phosphate 3-epimerase activity is a
L-ribulose-phosphate 4-epimerase activity is a
maltose epimerase activity is a
N-acylglucosamine 2-epimerase activity is a
N-acylglucosamine-6-phosphate 2-epimerase activity is a
ribulose-phosphate 3-epimerase activity is a
UDP-4-keto-6-deoxy-glucose-3,5-epimerase activity is a
UDP-arabinose 4-epimerase activity is a
UDP-glucosamine 4-epimerase activity is a
UDP-glucose 4-epimerase activity is a
UDP-glucuronate 4-epimerase activity is a
UDP-glucuronate 5'-epimerase activity is a
UDP-N-acetylglucosamine 2-epimerase activity is a
UDP-N-acetylglucosamine 4-epimerase activity is a
racemase and epimerase activity, acting on hydroxy acids and derivatives is a
sulfoquinovose isomerase activity is a
thiocyanate isomerase activity is a
ligase activity is a
lyase activity is a
peptidoglycan muralytic activity is a
transferase activity is a
molecular transducer activity is a
nutrient reservoir activity is a
protein tag is a
small molecule sensor activity is a
structural molecule activity is a
transcription regulator activity is a
transporter activity is a