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Version 2014-12-22
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Details for 15-hydroxyprostaglandin-I dehydrogenase (NADP+) activity
1.1.1.231
Gene ontology ID
GO:0047033
Definition
Catalysis of the reaction: NADP(+) + prostaglandin I(2) = 15-dehydro-prostaglandin I(2) + H(+) + NADPH
Synonyms
1. (5Z,13E)-(15S)-6,9alpha-epoxy-11alpha,15-dihydroxyprosta-5,13-dienoate:NADP+ 15-oxidoreductase activity
2. NADP+-dependent PGI2-specific 15-hydroxyprostaglandin dehydrogenase activity
3. NADP-linked 15-hydroxyprostaglandin (prostacyclin) dehydrogenase activity
4. PG I2 dehydrogenase activity
5. prostacyclin dehydrogenase activity
References
1. EC 1.1.1.231
2. RHEA: 21420
3. KEGG REACTION: R03520
4. MetaCyc 1.1.1.231-RXN
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