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Gene ontology
Version 2014-12-22
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Details for prostaglandin-F synthase activity
1.1.1.188
Gene ontology ID
GO:0047017
Definition
Catalysis of the reaction: NADP+ + (5Z,13E)-(15S)-9-alpha,11-alpha,15-trihydroxyprosta-5,13-dienoate = NADPH + H+ + (5Z,13E)-(15S)-9-alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate
Synonyms
1. (5Z,13E)-(15S)-9alpha,11alpha,15-trihydroxyprosta-5,13-dienoate:NADP+ 11-oxidoreductase activity
2. NADPH-dependent prostaglandin D2 11-keto reductase activity
3. PGD(2) 11-ketoreductase activity
4. PGD2 11-ketoreductase activity
5. PGF synthetase activity
6. PGF2alpha synthetase activity
7. prostaglandin 11-keto reductase activity
8. prostaglandin 11-ketoreductase activity
9. prostaglandin D2-ketoreductase activity
10. prostaglandin F synthase activity
11. prostaglandin F synthetase activity
12. prostaglandin-D(2) 11-ketoreductase activity
13. prostaglandin-D(2) 11-reductase activity
14. prostaglandin-D(2) ketoreductase activity
15. prostaglandin-D2 11-ketoreductase activity
16. prostaglandin-D2 11-reductase activity
17. prostaglandin-D2 ketoreductase activity
18. prostaglandin-F synthetase activity
19. reductase, 15-hydroxy-11-oxoprostaglandin
20. synthetase, prostaglandin F2alpha
References
1. EC 1.1.1.188
2. MetaCyc 1.1.1.188-RXN
3. RHEA: 10140
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