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Version 2014-12-22
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Details for hydroxymethylglutaryl-CoA reductase activity
1.1.1.88
Gene ontology ID
GO:0042282
Definition
Catalysis of the reaction: (R)-mevalonate + CoA + 2 NAD(+) = (S)-3-hydroxy-3-methylglutaryl-CoA + 2 H(+) + 2 NADH
Synonyms
1. (R)-mevalonate:NAD+ oxidoreductase (CoA-acylating)
2. 3-hydroxy-3-methylglutaryl coenzyme A reductase activity
3. 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity
4. beta-hydroxy-beta-methylglutaryl CoA-reductase activity
5. beta-hydroxy-beta-methylglutaryl coenzyme A reductase activity
6. HMG-CoA reductase activity
7. hydroxymethylglutaryl coenzyme A reductase activity
8. hydroxymethylglutaryl-CoA reductase (NADH) activity
References
1. EC 1.1.1.88
2. RHEA: 14833
3. KEGG REACTION: R02081
4. MetaCyc HYDROXYMETHYLGLUTARYL-COA-REDUCTASE-RXN
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