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Version 2014-12-22
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Details for 13-prostaglandin reductase activity
1.3.1.48
Gene ontology ID
GO:0036132
Definition
Catalysis of the reaction: 15-keto-prostaglandin + NAD(P)H + H+ -> 13,14-dihydro-15-keto-prostaglandin + NAD(P)+. This reaction is the reduction of 15-keto-prostaglandin
Comment
Note that this is the reverse of the reaction described in '15-oxoprostaglandin 13-oxidase activity ; GO:0047522'.
Synonyms
1. 15-ketoprostaglandin delta13-reductase activity
2. 15-oxo-delta13-prostaglandin reductase activity
3. 15-oxoprostaglandin 13-reductase activity
4. delta13-15-ketoprostaglandin reductase activity
5. prostaglandin 13-reductase activity
6. prostaglandin delta13-reductase activity
References
1. EC 1.3.1.48
2. GOC: mw
3. KEGG REACTION: R04556
4. KEGG REACTION: R04557
5. PMID 17449869
6. Reactome: R-HSA-2161692 "15k-PGE2/F2a is reduced to dhk-PGE2/F2a by PTGR1"
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