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Gene ontology
Version 2014-12-22
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Details for tRNA splicing, via endonucleolytic cleavage and ligation
Gene ontology ID
GO:0006388
Definition
Splicing of tRNA substrates via recognition of the folded RNA structure that brings the 5' and 3' splice sites into proximity and cleavage of the RNA at both the 3' and 5' splice sites by an endonucleolytic mechanism, followed by ligation of the exons
Comment
Note that while typically associated with tRNA splicing, splicing via endonucleolytic cleavages and subsequent ligation of the free exon ends is known to be used for some non-tRNA substrates, e.g. HAC1 (YFL031W) in S. cerevisiae and an intron in the 23S rRNA of the Archaeal species Desulfurococcus mobilis.
Synonyms
1. tRNA-Y splicing
References
1. GOC: krc
2. ISBN 0879695897
3. PMID 9582290
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