Any feedback?
Please rate this page
(ontology.php)
(0/150)

BRENDA support

Ontology explorer

Gene ontology
Version 2014-12-22
use AND (NOT) or OR
use AND (NOT) or OR
restrict to BRENDA links:
Details for steroid 21-monooxygenase activity
1.14.14.16
Gene ontology ID
GO:0004509
Definition
Catalysis of the reaction: a steroid + donor-H2 + O2 = a 21-hydroxysteroid + acceptor + H2O
Synonyms
1. 21-hydroxylase activity
2. cytochrome P450 CYP21A1
3. cytochrome p450 XXIA1 activity
4. steroid 21-hydroxylase activity
5. steroid,hydrogen-donor:oxygen oxidoreductase (21-hydroxylating)
References
1. EC 1.14.14.16
2. MetaCyc STEROID-21-MONOOXYGENASE-RXN
3. Reactome: R-HSA-193964 "CYP21A2 21-hydroxylates PROG"
4. Reactome: R-HSA-193981 "CYP21A2 oxidises 17HPROG"
5. Reactome: R-HSA-5601976 "Defective CYP21A2 does not 21-hydroxylate PROG"
Legend
is an element of the parent element
is a part of the parent element
is related to the parent element
derives from the parent element
// at least 1 tissue/ enzyme/ localization link in this branch
// tissue/ enzyme/ localization link to BRENDA
Condensed Tree View
Gene ontology
biological_process is a
metabolic process is a
oxidation-reduction process is a
oxidoreductase activity part of
monooxygenase activity is a
steroid hydroxylase activity is a
steroid 21-monooxygenase activity is a
Tree view
Gene ontology
biological_process is a
behavior is a
biological adhesion is a
biological phase is a
biological regulation is a
biomineralization is a
carbohydrate utilization is a
carbon utilization is a
cellular process is a
detoxification is a
developmental process is a
growth is a
immune system process is a
interspecies interaction between organisms is a
intraspecies interaction between organisms is a
localization is a
locomotion is a
metabolic process is a
adaptive thermogenesis is a
ATP metabolic process is a
biosynthetic process is a
catabolic process is a
collagen metabolic process is a
demethylation is a
glycosylation is a
hydrogen metabolic process is a
methylation is a
multi-organism metabolic process is a
NAD metabolic process is a
NADH metabolic process is a
NADP metabolic process is a
nitrogen compound metabolic process is a
organic substance metabolic process is a
oxidation-reduction process is a
iodide oxidation is a
oxidative deethylation is a
oxidoreductase activity part of
1,1,1-trichloroethane reductive dehalogenase activity is a
1,1,2-trichloroethene reductive dehalogenase activity is a
1,1-dichloro-2,2-bis(4-chlorophenyl)ethene dehalogenase activity is a
1,1-dichloroethane reductive dehalogenase activity is a
1,2-dichloroethene reductive dehalogenase activity is a
2,4-dichloroaniline reductive dehalogenase activity is a
2,4-dichlorophenoxyacetate dehalogenase activity is a
2,5-dichlorohydroquinone reductive dehalogenase activity is a
2-chloro-N-isopropylacetanilide reductive dehalogenase activity is a
2-octaprenylphenol hydroxylase activity is a
2-octoprenyl-3-methyl-6-methoxy-1,4-benzoquinone hydroxylase activity is a
3,3',5,5'-tetrabromobisphenol A reductive dehalogenase activity is a
3,3',5-tribromobisphenol A reductive dehalogenase activity is a
3,3'-dibromobisphenol A reductive dehalogenase activity is a
3,8-divinyl protochlorophyllide a 8-vinyl reductase activity is a
3-monobromobisphenol A reductive dehalogenase activity is a
alpha-ketoacid dehydrogenase activity is a
arsenate reductase activity is a
chlorate reductase activity is a
chromate reductase activity is a
crotonyl-CoA reductase activity is a
delta1-piperideine-6-carboxylate dehydrogenase activity is a
dihydronicotinamide riboside quinone reductase activity is a
dihydropterin oxidase activity is a
dimethylarsinate reductase activity is a
dioxygenase activity is a
epoxyqueuosine reductase activity is a
fatty acid alpha-hydroxylase activity is a
geranylgeranyl reductase activity is a
glycyl-radical enzyme activating activity is a
heme-copper terminal oxidase activity is a
hydroxymethylbutenyl pyrophosphate reductase activity is a
malolactic enzyme activity is a
monooxygenase activity is a
2-hydroxyisobutyrate 3-monooxygenase activity is a
2-hydroxypyridine 5-monooxygenase activity is a
20-aldehyde-leukotriene B4 20-monooxygenase activity is a
3-hydroxybenzoate 2-monooxygenase activity is a
4-chlorophenoxyacetate monooxygenase activity is a
4-ketotorulene 3-hydroxylase activity is a
4-methoxybenzoate monooxygenase (O-demethylating) activity is a
4-nitrocatechol 4-monooxygenase activity is a
adonirubin 3-hydroxylase activity is a
all-trans retinoic acid 18-hydroxylase activity is a
alpha-pinene monooxygenase activity is a
ammonia monooxygenase activity is a
androst-4-ene-3,17-dione monooxygenase activity is a
arachidonic acid monooxygenase activity is a
beta-carotene 3-hydroxylase activity is a
beta-cryptoxanthin hydroxylase activity is a
canthaxanthin 3-hydroxylase activity is a
carotene beta-ring hydroxylase activity is a
carotene epsilon hydroxylase activity is a
coumarin 7-hydroxylase activity is a
deoxyhypusine monooxygenase activity is a
dibenzothiophene-5,5-dioxide monooxygenase activity is a
echinenone 3-hydroxylase activity is a
estradiol 6-beta-monooxygenase activity is a
eupatolide synthase activity is a
fatty acid in-chain hydroxylase activity is a
ferulate 5-hydroxylase activity is a
germacrene A hydroxylase activity is a
jasmonoyl-isoleucine-12-hydroxylase activity is a
linalool 8-monooxygenase activity is a
linoleic acid epoxygenase activity is a
luciferin monooxygenase activity is a
methyl tertiary butyl ether 3-monooxygenase activity is a
naphthalene hydroxylase activity is a
nitrilotriacetate monooxygenase activity is a
ornithine N5-monooxygenase activity is a
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen is a
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen is a
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen is a
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen is a
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen is a
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen is a
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases) is a
p-coumarate 3-hydroxylase activity is a
phylloquinone monooxygenase (2,3-epoxidizing) activity is a
progesterone 11-alpha-monooxygenase activity is a
progesterone monooxygenase activity is a
retinoic acid 4-hydroxylase activity is a
secalciferol 1-monooxygenase activity is a
steroid 9-alpha-monooxygenase activity is a
steroid hydroxylase activity is a
cholesterol 25-hydroxylase activity is a
cholesterol 26-hydroxylase activity is a
ecdysone 20-monooxygenase activity is a
ecdysteroid 2-hydroxylase activity is a
ecdysteroid 22-hydroxylase activity is a
ecdysteroid 25-hydroxylase activity is a
estrogen 16-alpha-hydroxylase activity is a
estrogen 2-hydroxylase activity is a
oxysterol 7-alpha-hydroxylase activity is a
steroid 17-alpha-monooxygenase activity is a
steroid 21-monooxygenase activity is a
steroid 22-alpha hydroxylase activity is a
steroid 7-alpha-hydroxylase activity is a
sterol 12-alpha-hydroxylase activity is a
testosterone 15-alpha-hydroxylase activity is a
testosterone 16-alpha-hydroxylase activity is a
testosterone 6-beta-hydroxylase activity is a
tert-butanol 2-monooxygenase activity is a
testosterone 16-beta-hydroxylase activity is a
thalianol hydroxylase activity is a
thiophene-2-carbonyl-CoA monooxygenase activity is a
tryptamine 4-monooxygenase activity is a
vitamin D 23-hydroxylase activity is a
vitamin D 24-hydroxylase activity is a
vitamin D 25-hydroxylase activity is a
NADPH-adrenodoxin reductase activity is a
NADPH:sulfur oxidoreductase activity is a
ortho-trichlorophenol reductive dehalogenase activity is a
oxidoreductase activity, acting on a heme group of donors is a
oxidoreductase activity, acting on a sulfur group of donors is a
oxidoreductase activity, acting on CH or CH2 groups is a
oxidoreductase activity, acting on CH-OH group of donors is a
oxidoreductase activity, acting on diphenols and related substances as donors is a
oxidoreductase activity, acting on halogen in donors is a
oxidoreductase activity, acting on hydrogen as donor is a
oxidoreductase activity, acting on iron-sulfur proteins as donors is a
oxidoreductase activity, acting on NAD(P)H is a
oxidoreductase activity, acting on other nitrogenous compounds as donors is a
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen is a
oxidoreductase activity, acting on peroxide as acceptor is a
oxidoreductase activity, acting on phosphorus or arsenic in donors is a
oxidoreductase activity, acting on reduced flavodoxin as donor is a
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen is a
oxidoreductase activity, acting on superoxide radicals as acceptor is a
oxidoreductase activity, acting on the aldehyde or oxo group of donors is a
oxidoreductase activity, acting on the CH-CH group of donors is a
oxidoreductase activity, acting on the CH-NH group of donors is a
oxidoreductase activity, acting on the CH-NH2 group of donors is a
oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond is a
oxidoreductase activity, oxidizing metal ions is a
oxygen evolving activity is a
perchlorate reductase activity is a
phthalate dioxygenase reductase activity is a
pyrogallol hydroxytransferase activity is a
reduced coenzyme F420 dehydrogenase activity is a
reduced coenzyme F420 oxidase activity is a
reduced coenzyme F420:quinone oxidoreductase activity is a
selenate reductase activity is a
sphingosine hydroxylase activity is a
steroid dehydrogenase activity is a
sulfur oxygenase reductase activity is a
sulfur reductase activity is a
tetrachloroethene reductive dehalogenase activity is a
tetrahydrothiophene 1-oxide reductase activity is a
thyroxine 5'-deiodinase activity is a
thyroxine 5-deiodinase activity is a
trimethylarsine oxidase activity is a
tyramine-beta hydroxylase activity is a
uracil oxygenase activity is a
vinyl chloride reductive dehalogenase activity is a
violaxanthin de-epoxidase activity is a
thioredoxin reduction is a
pigment metabolic process is a
primary metabolic process is a
respiratory burst is a
secondary metabolic process is a
small molecule metabolic process is a
tartrate metabolic process is a
tyrocidine metabolic process is a
multi-organism process is a
multicellular organismal process is a
pigmentation is a
reproduction is a
response to stimulus is a
rhythmic process is a
signaling is a
cellular_component is a
molecular_function is a