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Gene ontology
Version 2014-12-22
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Details for diphosphomevalonate decarboxylase activity
4.1.1.33
Gene ontology ID
GO:0004163
Definition
Catalysis of the reaction: (R)-5-diphosphomevalonate + ATP = ADP + CO(2) + H(+) + isopentenyl diphosphate + phosphate
Synonyms
1. 5-pyrophosphomevalonate decarboxylase activity
2. ATP:(R)-5-diphosphomevalonate carboxy-lyase (adding ATP; isopentenyl-diphosphate-forming)
3. ATP:(R)-5-diphosphomevalonate carboxy-lyase (dehydrating)
4. mevalonate 5-diphosphate decarboxylase activity
5. mevalonate diphosphate decarboxylase activity
6. mevalonate pyrophosphate decarboxylase activity
7. mevalonate-5-pyrophosphate decarboxylase activity
8. pyrophosphomevalonate decarboxylase activity
9. pyrophosphomevalonic acid decarboxylase activity
References
1. EC 4.1.1.33
2. RHEA: 23732
3. KEGG REACTION: R01121
4. MetaCyc DIPHOSPHOMEVALONTE-DECARBOXYLASE-RXN
5. Reactome: R-HSA-191414 "MVD decarboxylates MVA5PP to IPPP"
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