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Version 2014-12-22
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Details for tubulin-tyrosine ligase activity
6.3.2.25
Gene ontology ID
GO:0004835
Definition
Catalysis of the reaction: ATP + detyrosinated alpha-tubulin + L-tyrosine = alpha-tubulin + ADP + phosphate
Synonyms
1. alpha-tubulin:L-tyrosine ligase (ADP-forming)
2. TTL activity
3. tubulinyl-tyrosine ligase activity
References
1. EC 6.3.2.25
2. MetaCyc 6.3.2.25-RXN
3. Reactome: R-HSA-8955706 "TTL ligates L-Tyr to the carboxy terminus of alpha-tubulin"
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