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Gene ontology
Version 2014-12-22
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Details for base J metabolic process
Gene ontology ID
GO:0070580
Definition
The chemical reactions and pathways involving base J (beta-D-glucosyl-hydroxymethyluracil), a hypermodified thymidine residue found in the genome of kinetoplastid parasites. This modified base is localized primarily to repetitive DNA, namely the telomeres, and is implicated in the regulation of antigenic variation. The base is synthesized in a two-step pathway. Initially, a thymidine residue in DNA is hydroxylated by a thymidine hydroxylase (TH) to form the intermediate hydroxymethyluracil, which is then glucosylated to form base J
Synonyms
1. base J metabolism
2. beta-D-glucosyl-HOMedU metabolic process
3. beta-D-glucosyl-hydroxymethyluracil metabolism
References
1. PMID 19114062
Legend
is an element of the parent element
is a part of the parent element
is related to the parent element
derives from the parent element
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Condensed Tree View
Gene ontology
biological_process is a
cellular process is a
cellular metabolic process is a
cellular aromatic compound metabolic process is a
nucleobase-containing compound metabolic process is a
nucleic acid metabolic process is a
DNA metabolic process is a
DNA modification is a
base J metabolic process is a
Tree view
Gene ontology
biological_process is a
behavior is a
biological adhesion is a
biological phase is a
biological regulation is a
biomineralization is a
carbohydrate utilization is a
carbon utilization is a
cellular process is a
actin filament-based process is a
cell activation is a
cell adhesion molecule production is a
cell aggregation is a
cell communication is a
cell cycle is a
cell death is a
cell division is a
cell growth is a
cell killing is a
cell population proliferation is a
cell recognition is a
cell wall organization or biogenesis is a
cell-cell fusion is a
cellular component organization or biogenesis is a
cellular detoxification is a
cellular developmental process is a
cellular localization is a
cellular metabolic process is a
bioluminescence is a
cellular alcohol metabolic process is a
cellular aldehyde metabolic process is a
cellular alkane metabolic process is a
cellular alkene metabolic process is a
cellular alkyne metabolic process is a
cellular aromatic compound metabolic process is a
(+)-kotanin metabolic process is a
2,5-dihydroxypyridine metabolic process is a
3-(3-hydroxy)phenylpropionate metabolic process is a
3-methylquinoline metabolic process is a
5-methylcytosine metabolic process is a
aromatic amino acid family metabolic process is a
aromatic compound biosynthetic process is a
aromatic compound catabolic process is a
aromatic primary alcohol metabolic process is a
benzene-containing compound metabolic process is a
carbazole metabolic process is a
cocaine metabolic process is a
coniferin metabolic process is a
daunorubicin metabolic process is a
demethylkotanin metabolic process is a
dibenzo-p-dioxin metabolic process is a
dibenzofuran metabolic process is a
doxorubicin metabolic process is a
epothilone metabolic process is a
fluorene metabolic process is a
imidazole-containing compound metabolic process is a
indole-containing compound metabolic process is a
isoquinoline alkaloid metabolic process is a
kynurenic acid metabolic process is a
naphthalene-containing compound metabolic process is a
nicotinate metabolic process is a
nucleobase-containing compound metabolic process is a
GDP-alpha-D-mannosylchitobiosyldiphosphodolichol metabolic process is a
nucleic acid metabolic process is a
DNA metabolic process is a
base-excision repair, AP site formation is a
base-excision repair, base-free sugar-phosphate removal is a
base-excision repair, gap-filling is a
deoxyribonuclease activity part of
DNA excision is a
DNA integration is a
DNA ligation is a
DNA modification is a
base J metabolic process is a
DNA ADP-ribosylation is a
DNA alkylation is a
DNA dealkylation is a
DNA deamination is a
DNA methylation or demethylation is a
DNA restriction-modification system is a
DNA recombination is a
DNA repair is a
G-quadruplex DNA formation is a
heteroduplex formation is a
programmed DNA elimination is a
nucleic acid phosphodiester bond hydrolysis is a
RNA metabolic process is a
nucleobase-containing small molecule metabolic process is a
polynucleotide dephosphorylation is a
ommochrome metabolic process is a
orlandin metabolic process is a
phenanthrene metabolic process is a
phenol-containing compound metabolic process is a
phenylpropanoid metabolic process is a
picolinic acid metabolic process is a
pteridine-containing compound metabolic process is a
purine-containing compound metabolic process is a
pyridine metabolic process is a
pyridoxamine metabolic process is a
pyridoxine metabolic process is a
s-triazine compound metabolic process is a
sterigmatocystin metabolic process is a
stilbene metabolic process is a
tetrapyrrole metabolic process is a
thiamine diphosphate metabolic process is a
thiamine-containing compound metabolic process is a
thiazole metabolic process is a
verruculogen metabolic process is a
vibriobactin metabolic process is a
cellular biosynthetic process is a
cellular carbohydrate metabolic process is a
cellular catabolic process is a
cellular ketone body metabolic process is a
cellular ketone metabolic process is a
cellular lipid metabolic process is a
cellular macromolecule metabolic process is a
cellular metabolic compound salvage is a
cellular modified amino acid metabolic process is a
cellular nitrogen compound metabolic process is a
cellular organohalogen metabolic process is a
chemosynthesis is a
cofactor metabolic process is a
drug metabolic process is a
generation of precursor metabolites and energy is a
heterocycle metabolic process is a
hydroperoxide metabolic process is a
metabolite repair is a
mucilage metabolic process is a
one-carbon metabolic process is a
organic acid metabolic process is a
organometal metabolic process is a
phosphorus metabolic process is a
photosynthesis is a
prenylation is a
reactive oxygen species metabolic process is a
selenium compound metabolic process is a
sulfur compound metabolic process is a
toxin metabolic process is a
xenobiotic metabolic process is a
cellular pigmentation is a
cellular process involved in reproduction in multicellular organism is a
cellular response to stimulus is a
chromosome segregation is a
cytolysis is a
DNA clamp unloading is a
ensheathment of neurons is a
establishment or maintenance of cell polarity is a
establishment or maintenance of cell type involved in phenotypic switching is a
export from cell is a
intercellular transport is a
intermediate filament-based process is a
light absorption is a
localization of cell is a
membrane docking is a
microtubule organizing center localization is a
microtubule-based process is a
movement of cell or subcellular component is a
multi-organism cellular process is a
phenotypic switching is a
plasmid maintenance is a
process utilizing autophagic mechanism is a
protein folding is a
protein unfolding is a
RNA folding is a
signaling receptor ligand precursor processing is a
stomatal movement is a
syncytium formation is a
transmembrane transport is a
transposition is a
vacuolar transport is a
vesicle-mediated transport is a
detoxification is a
developmental process is a
growth is a
immune system process is a
interspecies interaction between organisms is a
intraspecies interaction between organisms is a
localization is a
locomotion is a
metabolic process is a
multi-organism process is a
multicellular organismal process is a
pigmentation is a
reproduction is a
response to stimulus is a
rhythmic process is a
signaling is a
cellular_component is a
molecular_function is a
binding is a
catalytic activity is a
catalytic activity, acting on a protein is a
catalytic activity, acting on DNA is a
catalytic activity, acting on RNA is a
cyclase activity is a
hydrolase activity is a
beta-alanyl-dopamine hydrolase activity is a
beta-alanyl-histamine hydrolase activity is a
coenzyme F390-A hydrolase activity is a
coenzyme F390-G hydrolase activity is a
deacetylase activity is a
deaminase activity is a
hydrolase activity, acting on acid anhydrides is a
hydrolase activity, acting on acid carbon-carbon bonds is a
hydrolase activity, acting on acid carbon-phosphorus bonds is a
hydrolase activity, acting on acid halide bonds is a
hydrolase activity, acting on acid phosphorus-nitrogen bonds is a
hydrolase activity, acting on acid sulfur-nitrogen bonds is a
hydrolase activity, acting on acid sulfur-sulfur bonds is a
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds is a
hydrolase activity, acting on carbon-sulfur bonds is a
hydrolase activity, acting on ester bonds is a
aspartyl esterase activity is a
carboxylic ester hydrolase activity is a
DNA-3'-diphospho-5'-guanosine diphosphatase is a
enterochelin esterase activity is a
indole-3-acetyl-beta-1-D-glucose hydrolase activity is a
indole-3-acetyl-beta-4-D-glucose hydrolase activity is a
lipase activity is a
phosphoric ester hydrolase activity is a
sulfuric ester hydrolase activity is a
thiolester hydrolase activity is a
2,4,4-trimethyl-3-oxopentanoyl-CoA thioesterase activity is a
2-oxoglutaryl-CoA thioesterase activity is a
3-isopropylbut-3-enoyl-CoA thioesterase activity is a
3-oxo-dodecanoyl-ACP hydrolase activity is a
3-oxo-myristoyl-ACP hydrolase activity is a
3-oxo-myristoyl-CoA hydrolase activity is a
3-oxo-palmitoyl-ACP hydrolase activity is a
3-oxoacyl-CoA hydrolase activity is a
acyl-[acyl-carrier-protein] hydrolase activity is a
CoA hydrolase activity is a
(S)-methylmalonyl-CoA hydrolase activity is a
1,4-dihydroxy-2-naphthoyl-CoA thioesterase activity is a
3-hydroxyisobutyryl-CoA hydrolase activity is a
4-hydroxybenzoyl-CoA thioesterase activity is a
acetoacetyl-CoA hydrolase activity is a
acetyl-CoA hydrolase activity is a
acyl-CoA hydrolase activity is a
bile-acid-CoA hydrolase activity is a
choloyl-CoA hydrolase activity is a
formyl-CoA hydrolase activity is a
hydroxymethylglutaryl-CoA hydrolase activity is a
phenylacetyl-CoA hydrolase activity is a
succinyl-CoA hydrolase activity is a
glutathione thiolesterase activity is a
hydroxyacylglutathione hydrolase activity is a
myristoyl-CoA hydrolase activity is a
S-formylglutathione hydrolase activity is a
S-succinylglutathione hydrolase activity is a
[citrate-(pro-3S)-lyase] thiolesterase activity is a
versiconal hemiacetal acetate esterase activity is a
hydrolase activity, acting on ether bonds is a
hydrolase activity, acting on glycosyl bonds is a
isomerase activity is a
ligase activity is a
lyase activity is a
peptidoglycan muralytic activity is a
transferase activity is a
molecular transducer activity is a
nutrient reservoir activity is a
protein tag is a
small molecule sensor activity is a
structural molecule activity is a
transcription regulator activity is a
transporter activity is a