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Gene ontology
Version 2014-12-22
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Details for serine-type peptidase activity
Gene ontology ID
GO:0008236
Definition
Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine)
Synonyms
1. serine protease activity
References
1. http merops.sanger.ac.uk/about/glossary.htm#CATTYPE
2. ISBN 0716720094
3. Reactome: R-HSA-1461993 "pro-HD5 is cleaved by trypsin"
4. Reactome: R-HSA-2022383 "Chymase hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8)"
5. Reactome: R-HSA-3132753 "Pancreatic proteases degrade TCN1:Cbl"
6. Reactome: R-HSA-6801766 "Trypsin cleaves REG3A or REG3G to generate REG3A,G(38-175)"
Legend
is an element of the parent element
is a part of the parent element
is related to the parent element
derives from the parent element
// at least 1 tissue/ enzyme/ localization link in this branch
// tissue/ enzyme/ localization link to BRENDA
Condensed Tree View
Gene ontology
biological_process is a
metabolic process is a
nitrogen compound metabolic process is a
organonitrogen compound metabolic process is a
protein metabolic process is a
proteolysis is a
peptidase activity part of
peptidase activity, acting on L-amino acid peptides is a
serine-type peptidase activity is a
Tree view
Gene ontology
biological_process is a
behavior is a
biological adhesion is a
biological phase is a
biological regulation is a
biomineralization is a
carbohydrate utilization is a
carbon utilization is a
cellular process is a
detoxification is a
developmental process is a
growth is a
immune system process is a
interspecies interaction between organisms is a
intraspecies interaction between organisms is a
localization is a
locomotion is a
metabolic process is a
adaptive thermogenesis is a
ATP metabolic process is a
biosynthetic process is a
catabolic process is a
collagen metabolic process is a
demethylation is a
glycosylation is a
hydrogen metabolic process is a
methylation is a
multi-organism metabolic process is a
NAD metabolic process is a
NADH metabolic process is a
NADP metabolic process is a
nitrogen compound metabolic process is a
aldoxime metabolic process is a
ammonia oxidation is a
ammonium ion metabolic process is a
betaine aldehyde metabolic process is a
nitrogen cycle metabolic process is a
organonitrogen compound metabolic process is a
alkaloid metabolic process is a
amine metabolic process is a
aminoglycan metabolic process is a
N',N'',N'''-triacetylfusarinine C metabolic process is a
nitrile metabolic process is a
primary amino compound metabolic process is a
protein metabolic process is a
amyloid precursor protein metabolic process is a
cytochrome metabolic process is a
cytokine metabolic process is a
insulin metabolic process is a
lipoprotein metabolic process is a
protein activation cascade is a
protein maturation is a
protein modification process is a
proteolysis is a
membrane protein proteolysis is a
peptidase activity part of
isopeptidase activity is a
oligopeptidase activity is a
peptidase activity, acting on D-amino acid peptides is a
peptidase activity, acting on L-amino acid peptides is a
aspartic-type peptidase activity is a
ATP-dependent peptidase activity is a
cysteine-type peptidase activity is a
endopeptidase activity is a
exopeptidase activity is a
glutamic-type peptidase activity is a
metallopeptidase activity is a
serine-type peptidase activity is a
threonine-type peptidase activity is a
self proteolysis is a
wybutosine metabolic process is a
reactive nitrogen species metabolic process is a
organic substance metabolic process is a
oxidation-reduction process is a
pigment metabolic process is a
primary metabolic process is a
respiratory burst is a
secondary metabolic process is a
small molecule metabolic process is a
tartrate metabolic process is a
tyrocidine metabolic process is a
multi-organism process is a
multicellular organismal process is a
pigmentation is a
reproduction is a
response to stimulus is a
rhythmic process is a
signaling is a
cellular_component is a
molecular_function is a
binding is a
catalytic activity is a
catalytic activity, acting on a protein is a
catalytic activity, acting on DNA is a
catalytic activity, acting on RNA is a
cyclase activity is a
hydrolase activity is a
beta-alanyl-dopamine hydrolase activity is a
beta-alanyl-histamine hydrolase activity is a
coenzyme F390-A hydrolase activity is a
coenzyme F390-G hydrolase activity is a
deacetylase activity is a
deaminase activity is a
hydrolase activity, acting on acid anhydrides is a
hydrolase activity, acting on acid carbon-carbon bonds is a
hydrolase activity, acting on acid carbon-phosphorus bonds is a
hydrolase activity, acting on acid halide bonds is a
hydrolase activity, acting on acid phosphorus-nitrogen bonds is a
hydrolase activity, acting on acid sulfur-nitrogen bonds is a
hydrolase activity, acting on acid sulfur-sulfur bonds is a
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds is a
hydrolase activity, acting on carbon-sulfur bonds is a
hydrolase activity, acting on ester bonds is a
aspartyl esterase activity is a
carboxylic ester hydrolase activity is a
DNA-3'-diphospho-5'-guanosine diphosphatase is a
enterochelin esterase activity is a
indole-3-acetyl-beta-1-D-glucose hydrolase activity is a
indole-3-acetyl-beta-4-D-glucose hydrolase activity is a
lipase activity is a
phosphoric ester hydrolase activity is a
sulfuric ester hydrolase activity is a
thiolester hydrolase activity is a
2,4,4-trimethyl-3-oxopentanoyl-CoA thioesterase activity is a
2-oxoglutaryl-CoA thioesterase activity is a
3-isopropylbut-3-enoyl-CoA thioesterase activity is a
3-oxo-dodecanoyl-ACP hydrolase activity is a
3-oxo-myristoyl-ACP hydrolase activity is a
3-oxo-myristoyl-CoA hydrolase activity is a
3-oxo-palmitoyl-ACP hydrolase activity is a
3-oxoacyl-CoA hydrolase activity is a
acyl-[acyl-carrier-protein] hydrolase activity is a
CoA hydrolase activity is a
(S)-methylmalonyl-CoA hydrolase activity is a
1,4-dihydroxy-2-naphthoyl-CoA thioesterase activity is a
3-hydroxyisobutyryl-CoA hydrolase activity is a
4-hydroxybenzoyl-CoA thioesterase activity is a
acetoacetyl-CoA hydrolase activity is a
acetyl-CoA hydrolase activity is a
acyl-CoA hydrolase activity is a
bile-acid-CoA hydrolase activity is a
choloyl-CoA hydrolase activity is a
formyl-CoA hydrolase activity is a
hydroxymethylglutaryl-CoA hydrolase activity is a
phenylacetyl-CoA hydrolase activity is a
succinyl-CoA hydrolase activity is a
glutathione thiolesterase activity is a
hydroxyacylglutathione hydrolase activity is a
myristoyl-CoA hydrolase activity is a
S-formylglutathione hydrolase activity is a
S-succinylglutathione hydrolase activity is a
[citrate-(pro-3S)-lyase] thiolesterase activity is a
versiconal hemiacetal acetate esterase activity is a
hydrolase activity, acting on ether bonds is a
hydrolase activity, acting on glycosyl bonds is a
isomerase activity is a
ligase activity is a
lyase activity is a
peptidoglycan muralytic activity is a
transferase activity is a
molecular transducer activity is a
nutrient reservoir activity is a
protein tag is a
small molecule sensor activity is a
structural molecule activity is a
transcription regulator activity is a
transporter activity is a