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Gene ontology
Version 2014-12-22
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Details for tRNA dimethylallyltransferase activity
2.5.1.75
Gene ontology ID
GO:0052381
Definition
Catalysis of the reaction: dimethylallyl diphosphate + tRNA = diphosphate + tRNA containing 6-dimethylallyladenosine
Comment
Note that this activity was formerly know in GO and EC as 'tRNA isopentenyltransferase' (EC:2.5.1.8, GO:0004811), but it is now known that dimethylallyl diphosphate, rather than isopentenyl diphosphate, is the substrate.
Synonyms
1. dimethylallyl-diphosphate:tRNA dimethylallyltransferase activity
2. tRNA isopentenyltransferase activity
3. tRNA prenyltransferase activity
References
1. EC 2.5.1.75
2. MetaCyc RXN0-6274
3. Reactome: R-HSA-6784462 "TRIT1 transfers dimethylallyl group to adenosine-37 of tRNAs"
4. Reactome: R-HSA-6787567 "TRIT1 transfers dimethylallyl group to adenosine-37 of tRNA(Ser)"
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