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Ontology explorer

Gene ontology
Version 2014-12-22
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Details for gamma-glutamyl carboxylase activity
4.1.1.90
Gene ontology ID
GO:0008488
Definition
Catalysis of the reaction: peptidyl-glutamate + reduced vitamin K + CO2 + O2 = peptidyl-gamma-carboxyglutamate + vitamin K epoxide
References
1. PMID 18374194
2. EC 4.1.1.90
3. Reactome: R-HSA-159752 "GGCX gamma-carboxylates PROS1(25-676) (pro-protein S)"
4. Reactome: R-HSA-159761 "GGCX gamma-carboxylates F7(21-466) (pro-factor VII)"
5. Reactome: R-HSA-159795 "GGCX gamma-carboxylates 3D-PROC(33-197) (pro-protein C light chain)"
6. Reactome: R-HSA-159803 "GGCX gamma-carboxylates 3D-F9(29-461) (pro-factor IX)"
7. Reactome: R-HSA-159819 "GGCX gamma-carboxylates 3D-F10(32-179) (pro-factor X light chain)"
8. Reactome: R-HSA-159826 "GGCX gamma-carboxylates F2(25-622) (pro-prothrombin)"
9. Reactome: R-HSA-163810 "GGCX gamma-carboxylates GAS6(31-691) (pro-GAS6)"
10. Reactome: R-HSA-163820 "GGCX gamma-carboxylates PROZ(24-400) (pro-protein Z)"
11. Reactome: R-HSA-6807214 "GGCX gamma-carboxylates BGLAP(24-100) (pro-osteocalcin)"
12. RHEA: 45140
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Gene ontology