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Gene ontology
Version 2014-12-22
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Details for telomere maintenance via telomere trimming
Gene ontology ID
GO:0090737
Definition
A process that contributes to the maintenance of proper telomeric length and structure via the activation of telomere shortening pathways that compensate telomerase-dependent excessive telomere elongation. Telomere attrition is mediated by a mechanism which involves the generation of single-stranded C-rich telomeric DNA, and the formation and removal of double-stranded telomeric circular DNA (T-circles). Telomere trimming is an independent pathway to recombination-mediated telomere elongation and the well-documented gradual telomere attrition that accompanies cellular replication
References
1. GOC: BHF
2. GOC: BHF telomere
3. GOC: nc
4. PMID 27918544
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