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Gene ontology
Version 2014-12-22
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Details for base-excision repair, AP site formation
Gene ontology ID
GO:0006285
Definition
The formation of an AP site, a deoxyribose sugar with a missing base, by DNA glycosylase which recognizes an altered base in DNA and catalyzes its hydrolytic removal. This sugar phosphate is the substrate recognized by the AP endonuclease, which cuts the DNA phosphodiester backbone at the 5' side of the altered site to leave a gap which is subsequently repaired
References
1. ISBN 0815316194
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