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Gene ontology
Version 2014-12-22
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Details for translational attenuation
Gene ontology ID
GO:0009386
Definition
Translational attenuation is a regulatory mechanism analogous to ribosome-mediated transcriptional attenuation. The system requires the presence of a short ORF, called a leader peptide, encoded in the mRNA upstream of the ribosome-binding site and start codon of the gene whose translation is to be regulated. Certain conditions, such as presence of the antibiotic tetracycline in bacteria or amino acid starvation, may cause slowing or stalling of the ribosome translating the leader peptide. The stalled ribosome masks a region of the mRNA and affects which of two alternative mRNA folded structures will form, therefore controlling whether or not a ribosome will bind and initiate translation of the downstream gene. Translational attenuation is analogous to ribosome-mediated transcriptional attenuation, in which mRNA remodeling caused by ribosome stalling regulates transcriptional termination rather than translational initiation
References
1. PMID 15694341
2. PMID 15805513
Legend
is an element of the parent element
is a part of the parent element
is related to the parent element
derives from the parent element
// at least 1 tissue/ enzyme/ localization link in this branch
// tissue/ enzyme/ localization link to BRENDA
Condensed Tree View
Gene ontology
biological_process is a
biological regulation is a
regulation of biological process is a
regulation of cellular process is a
regulation of cellular metabolic process is a
regulation of cellular amide metabolic process is a
regulation of translation is a
translational attenuation is a
Tree view
Gene ontology
biological_process is a
behavior is a
biological adhesion is a
biological phase is a
biological regulation is a
negative regulation of phosphatidylcholine metabolic process is a
regulation of biological process is a
modulation of host virulence by virus is a
negative regulation of biological process is a
positive regulation of biological process is a
regulation of action potential is a
regulation of asexual reproduction is a
regulation of biomineralization is a
regulation of carbohydrate utilization is a
regulation of carbon utilization is a
regulation of cellular process is a
cell redox homeostasis is a
modulation by symbiont of host cellular process is a
regulation of actin filament-based process is a
regulation of binding of sperm to zona pellucida is a
regulation of cartilage condensation is a
regulation of cell activation is a
regulation of cell adhesion molecule production is a
regulation of cell aging is a
regulation of cell communication is a
regulation of cell cycle is a
regulation of cell death is a
regulation of cell differentiation is a
regulation of cell division is a
regulation of cell killing is a
regulation of cell population proliferation is a
regulation of cell wall organization or biogenesis is a
regulation of cellular component biogenesis is a
regulation of cellular component movement is a
regulation of cellular component organization is a
regulation of cellular localization is a
regulation of cellular metabolic process is a
positive regulation of glycine hydroxymethyltransferase activity is a
regulation of 17-methylnonadec-1-ene metabolic process is a
regulation of 18-methylnonadec-1-ene metabolic process is a
regulation of amylopectin metabolic process is a
regulation of auxin metabolic process is a
regulation of bile acid metabolic process is a
regulation of bioluminescence is a
regulation of cellular amide metabolic process is a
regulation of acyl-CoA biosynthetic process is a
regulation of amyloid-beta formation is a
regulation of antimicrobial peptide biosynthetic process is a
regulation of brevianamide F biosynthetic process is a
regulation of butyryl-CoA catabolic process to butanol is a
regulation of butyryl-CoA catabolic process to butyrate is a
regulation of cellular amide catabolic process is a
regulation of emericellamide biosynthetic process is a
regulation of gliotoxin biosynthetic process is a
regulation of glucosylceramide catabolic process is a
regulation of glutathione biosynthetic process is a
regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway is a
regulation of penicillin metabolic process is a
regulation of pentose-phosphate shunt is a
regulation of peptide hormone processing is a
regulation of pseurotin A biosynthetic process is a
regulation of siderophore biosynthetic process is a
regulation of sphingomyelin catabolic process is a
regulation of tensidol A biosynthetic process is a
regulation of tensidol B biosynthetic process is a
regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA is a
regulation of translation is a
circadian regulation of translation is a
regulation of cytoplasmic translation is a
regulation of mitochondrial translation is a
regulation of oskar mRNA translation is a
regulation of translation at synapse is a
regulation of translation by machinery localization is a
regulation of translation in response to stress is a
regulation of translation involved in anterior/posterior axis specification is a
regulation of translation involved in cellular response to UV is a
regulation of translation, ncRNA-mediated is a
regulation of translational elongation is a
regulation of translational initiation is a
rescue of stalled ribosome is a
translation regulator activity part of
translational attenuation is a
translational readthrough is a
regulation of urea metabolic process is a
regulation of cellular amine metabolic process is a
regulation of cellular biosynthetic process is a
regulation of cellular carbohydrate metabolic process is a
regulation of cellular catabolic process is a
regulation of cellular ketone metabolic process is a
regulation of cellular organohalogen metabolic process is a
regulation of cellular protein metabolic process is a
regulation of chitin metabolic process is a
regulation of cholesterol esterification is a
regulation of cofactor metabolic process is a
regulation of generation of precursor metabolites and energy is a
regulation of glucocorticoid metabolic process is a
regulation of glycoprotein metabolic process is a
regulation of heptadecane metabolic process is a
regulation of hexadecanal metabolic process is a
regulation of isoprenoid metabolic process is a
regulation of lipoprotein metabolic process is a
regulation of melanization defense response is a
regulation of membrane lipid metabolic process is a
regulation of methanofuran metabolic process is a
regulation of methanophenazine metabolic process is a
regulation of nitrate assimilation is a
regulation of nonadec-1-ene metabolic process is a
regulation of nucleobase-containing compound metabolic process is a
regulation of octadecene metabolic process is a
regulation of oxygen metabolic process is a
regulation of pentadecane metabolic process is a
regulation of phenylpropanoid metabolic process is a
regulation of phosphorus metabolic process is a
regulation of photorespiration is a
regulation of photosynthesis is a
regulation of phytoalexin metabolic process is a
regulation of pteridine metabolic process is a
regulation of reactive oxygen species metabolic process is a
regulation of receptor biosynthetic process is a
regulation of receptor recycling is a
regulation of sulfur metabolic process is a
regulation of tetrapyrrole metabolic process is a
regulation of thyroid hormone generation is a
regulation of toluene metabolic process is a
regulation of tridecane metabolic process is a
regulation of triglyceride metabolic process is a
regulation of cellular pH reduction is a
regulation of cellular response to alcohol is a
regulation of cellular response to alkaline pH is a
regulation of cellular response to drug is a
regulation of cellular response to gamma radiation is a
regulation of cellular response to growth factor stimulus is a
regulation of cellular response to insulin stimulus is a
regulation of cellular response to macrophage colony-stimulating factor stimulus is a
regulation of cellular response to manganese ion is a
regulation of cellular response to oxidopamine is a
regulation of cellular response to stress is a
regulation of cellular response to testosterone stimulus is a
regulation of cellular response to thapsigargin is a
regulation of cellular response to tunicamycin is a
regulation of cellular response to very-low-density lipoprotein particle stimulus is a
regulation of cellular response to X-ray is a
regulation of chromosome segregation is a
regulation of conjugation is a
regulation of cytolysis is a
regulation of establishment or maintenance of cell polarity is a
regulation of horizontal cell localization is a
regulation of membrane depolarization is a
regulation of microtubule-based process is a
regulation of myelination is a
regulation of peroxidase activity is a
regulation of phenotypic switching is a
regulation of protein folding is a
regulation of response to cell cycle checkpoint signaling is a
regulation of secretion by cell is a
regulation of single-species biofilm formation is a
regulation of stomatal movement is a
regulation of transmembrane transport is a
regulation of transposition is a
regulation of vacuolar transport is a
regulation of vesicle-mediated transport is a
signal transduction is a
regulation of circadian rhythm is a
regulation of developmental pigmentation is a
regulation of developmental process is a
regulation of estrogen receptor binding is a
regulation of growth is a
regulation of guanyl-nucleotide exchange factor activity is a
regulation of hemostasis is a
regulation of immune system process is a
regulation of interspecies interactions between organisms is a
regulation of localization is a
regulation of locomotion is a
regulation of membrane hyperpolarization is a
regulation of metabolic process is a
regulation of multi-organism process is a
regulation of multicellular organismal process is a
regulation of nitrogen utilization is a
regulation of phosphorus utilization is a
regulation of plasma lipoprotein particle levels is a
regulation of reproductive process is a
regulation of response to stimulus is a
regulation of signaling is a
regulation of sulfur utilization is a
regulation of biological quality is a
regulation of molecular function is a
biomineralization is a
carbohydrate utilization is a
carbon utilization is a
cellular process is a
detoxification is a
developmental process is a
growth is a
immune system process is a
interspecies interaction between organisms is a
intraspecies interaction between organisms is a
localization is a
locomotion is a
metabolic process is a
multi-organism process is a
multicellular organismal process is a
pigmentation is a
reproduction is a
response to stimulus is a
rhythmic process is a
signaling is a
cellular_component is a
molecular_function is a
binding is a
catalytic activity is a
catalytic activity, acting on a protein is a
catalytic activity, acting on DNA is a
catalytic activity, acting on RNA is a
cyclase activity is a
hydrolase activity is a
isomerase activity is a
ligase activity is a
lyase activity is a
peptidoglycan muralytic activity is a
transferase activity is a
Atg8 ligase activity is a
CDP-alcohol phosphotransferase activity is a
glucanosyltransferase activity is a
Kdo transferase activity is a
mannosylphosphate transferase activity is a
molybdopterin molybdotransferase activity is a
transferase activity, transferring acyl groups is a
transferase activity, transferring acyl groups other than amino-acyl groups is a
(Z)-3-hexen-1-ol acetyltransferase activity is a
13-hydroxylupinine O-tigloyltransferase activity is a
2,3-diaminopropionate N-oxalyltransferase activity is a
2,4,4-trimethyl-3-oxopentanoyl-CoA 2-C-propanoyl transferase activity is a
2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA C-acetyltransferase activity is a
2-alpha-hydroxytaxane 2-O-benzoyltransferase activity is a
2-ketobutyrate formate-lyase activity is a
2-methylhexanoyl-CoA C-acetyltransferase activity is a
2-phenylethanol acetyltransferase activity is a
3'-N-debenzoyl-2'-deoxytaxol N-benzoyltransferase activity is a
3-hydroxybutyryl-CoA thiolase activity is a
3-keto-5-aminohexanoate cleavage activity is a
3-ketopimelyl-CoA thiolase activity is a
3-oxo-arachidoyl-CoA synthase activity is a
3-oxo-cerotoyl-CoA synthase activity is a
3-oxo-lignoceronyl-CoA synthase activity is a
3-oxoadipyl-CoA thiolase activity is a
4-coumaroyl-CoA:cyanidin-3,5-diglucoside-6''-O-acyltransferase activity is a
4-coumaroyl-CoA:cyanidin-3-O-beta-D-glucoside-6''-O-acyltransferase activity is a
4-coumaroyl-CoA:pelargonidin-3-O-beta-D-glucoside-6''-O-acyltransferase activity is a
4-coumaroylhexanoylmethane synthase activity is a
4-methylumbelliferyl glucoside 6'-O-malonyltransferase activity is a
5-pentadecatrienylresorcinol synthase activity is a
6'-deoxychalcone synthase activity is a
6-(4-methyl-2-oxopentyl)-4-hydroxy-2-pyrone synthase activity is a
6-methylsalicylic acid synthase activity is a
8-amino-7-oxononanoate synthase activity is a
acetoacetyl-ACP synthase activity is a
acetyl-coenzyme A:acetyl alcohol acetyltransferase activity is a
acetyltransferase activity is a
acridone synthase activity is a
acrylate:acyl-coA CoA transferase activity is a
acyl coenzyme A: isopenicillin N acyltransferase activity is a
acyl-phosphate glycerol-3-phosphate acyltransferase activity is a
agmatine N4-coumaroyltransferase activity is a
alcohol O-cinnamoyltransferase activity is a
anthocyanidin 3-O-glucoside 6''-O-acyltransferase activity is a
anthocyanin 5-aromatic acyltransferase activity is a
anthocyanin 5-O-glucoside 6'''-O-malonyltransferase activity is a
anthocyanin 5-O-glucoside-4'''-O-malonyltransferase activity is a
anthocyanin 6''-O-malonyltransferase activity is a
anthranilate N-benzoyltransferase activity is a
arachidoyl-CoA:1-dodecanol O-acyltransferase activity is a
benzoyl acetate-CoA thiolase activity is a
beta-glucogallin O-galloyltransferase activity is a
beta-glucogallin-tetrakisgalloylglucose O-galloyltransferase activity is a
beta-ketoacyl-acyl-carrier-protein synthase II activity is a
beta-ketoacyl-acyl-carrier-protein synthase III activity is a
biphenyl synthase activity is a
bisdemethoxycurcumin synthase activity is a
butanoyltransferase activity is a
butyryl-CoA 2-C-propionyltransferase activity is a
C-acyltransferase activity is a
caffeoyl-CoA: alcohol caffeoyl transferase activity is a
caffeoyl-CoA:3-O-glucosyl-5-O-(caffeoylglucoside-3'-O-glucoside) 3'-O-hydroxycinnamoyltransferase activity is a
caffeoyl-CoA:delphinidin-3,5,3'-triglucoside 5-O-glucoside-6-O-hydroxycinnamoyltransferase activity is a
caffeoyl-CoA:delphinidin-3,5-diglucoside 5-O-glucoside-6-O-hydroxycinnamoyltransferase activity is a
caffeoyl-CoA:pelargonidin-3,5-diglucoside 5-O-glucoside-6-O-hydroxycinnamoyltransferase activity is a
caffeoyl-CoA:pelargonidin-3,5-diglucoside-6''-O-acyltransferase activity is a
caffeoyl-CoA:pelargonidin-3-O-beta-D-glucoside-6''-O-acyltransferase activity is a
caffeoyl-CoA:shikimate O-(hydroxycinnamoyl)transferase activity is a
chalcone synthase activity is a
CO-methylating acetyl-CoA synthase activity is a
curcumin synthase activity is a
cyanidin 3-O-glucoside 3'',6''-O-dimalonyltransferase activity is a
cyanidin 3-O-glucoside 6''-O-malonyltransferase activity is a
cyanidin 3-O-glucoside-(2''-O-xyloside) 6''-O-acyltransferase activity is a
cyanidin 3-O-glucoside-p-coumaroyltransferase activity is a
cyanidin 3-O-[2''-O-(2''-O-(sinapoyl) xylosyl) 6''-O-(p-coumaroyl) glucoside] 5-O-[6''-O-(malonyl) glucoside] sinapoyltransferase activity is a
cyanidin 3-O-[2''-O-(xylosyl)-6''-O-(p-coumaroyl) glucoside] 5-O-glucoside malonyltransferase activity is a
cyanidin 7-O-(6-O-(4-O-(glucosyl)-oxybenzoyl)-glucoside) acyltransferase (acyl-glucose dependent) activity is a
cyanidin 7-O-glucoside acyltransferase(acyl-glucose dependent) activity is a
cysteine-S-conjugate N-malonyl transferase activity is a
decanoyltransferase activity is a
delphinidin 7-O-(6-O-(4-O-(glucosyl)-oxybenzoyl)-glucoside) acyltransferase (acyl-glucose dependent activity is a
delphinidin 7-O-glucoside acyltransferase (acyl-glucose dependent) activity is a
demethoxycurcumin synthase is a
demethoxycurcumin synthase activity is a
demethoxycurcumin synthase activity from feruloylacetyl-CoA is a
diacylglycerol transacylase activity is a
dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity is a
erythronolide synthase activity is a
fatty acid synthase activity is a
fatty-acyl-[acp] elongase/decarboxylase activity is a
flavonol-3-O-triglucoside O-coumaroyltransferase activity is a
gamma-linolenate elongase activity is a
glutamine N-phenylacetyltransferase activity is a
glycero-3-phosphocholine acyltransferase activity is a
glycerophospholipid acyltransferase (CoA-dependent) activity is a
glycerophospholipid arachidonoyl-transferase (CoA-independent) activity is a
glycine N-benzoyltransferase activity is a
glycine N-choloyltransferase activity is a
heptadecanoyl-[acp] elongase/decarboxylase activity is a
hexanoyltransferase activity is a
hydroxycinnamoyltransferase activity is a
icosanoyl-CoA synthase activity is a
isocitrate O-dihydroxycinnamoyltransferase activity is a
keto acid formate lyase activity is a
lauroyltransferase activity is a
lecithin:11-cis retinol acyltransferase activity is a
lipoyl(octanoyl) transferase activity is a
lipoyltransferase activity is a
lovastatin nonaketide synthase activity is a
lysophospholipid acyltransferase activity is a
malonyl-malonyl acyl carrier protein-condensing enzyme activity is a
malonyltransferase activity is a
methione N-acyltransferase activity is a
mycocerosate synthase activity is a
mycothiol synthase activity is a
myristoyltransferase activity is a
N(6)-L-threonylcarbamoyladenine synthase activity is a
N-acyltransferase activity is a
naphthyl-2-oxomethyl-succinyl-CoA succinyl transferase activity is a
naringenin-chalcone synthase activity is a
norsolorinate anthrone synthase activity is a
O-acyltransferase activity is a
octanoyltransferase activity is a
omega-hydroxypalmitate O-sinapoyl transferase activity is a
ornithine N-benzoyltransferase activity is a
ornithine N-delta-acetyltransferase activity is a
p-coumaroyltriacetic acid lactone synthase activity is a
p-coumaroyltriacetic acid synthase activity is a
palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity is a
palmitoleoyltransferase activity is a
palmitoyl-[acp] elongase/decarboxylase activity is a
palmitoyltransferase activity is a
phenylacetyl-coenzyme A:glycine N-acyltransferase activity is a
phenylpropanoyltransferase activity is a
phloroisovalerophenone synthase activity is a
phosphate butyryltransferase activity is a
phosphate:acyl-[acyl carrier protein] acyltransferase activity is a
phosphinothricin N-acetyltransferase activity is a
pinosylvin synthase activity is a
piperidine N-piperoyltransferase activity is a
plasmalogen synthase activity is a
propionyl-CoA C2-trimethyltridecanoyltransferase activity is a
pyruvyltransferase activity is a
rosmarinate synthase activity is a
S-acyltransferase activity is a
sinapoyltransferase activity is a
sn-1-glycerol-3-phosphate C16:0-DCA-CoA acyl transferase activity is a
sn-2-glycerol-3-phosphate C16:0-CoA acyl transferase activity is a
sn-2-glycerol-3-phosphate C16:0-DCA-CoA acyl transferase activity is a
sn-2-glycerol-3-phosphate C22:0-DCA-CoA acyl transferase activity is a
sn-2-glycerol-3-phosphate omega-OH-C22:0-CoA acyl transferase activity is a
stearoyl-[acp] elongase/decarboxylase activity is a
succinyltransferase activity is a
tetrahydroxybenzophenone synthase activity is a
tetraketide alpha-pyrone synthase activity is a
trehalose O-mycolyltransferase activity is a
trihydroxybenzophenone synthase activity is a
trihydroxystilbene synthase activity is a
tyramine N-feruloyltransferase activity is a
UDP-3-O-(R-3-hydroxymyristoyl)-glucosamine N-acyltransferase activity is a
very-long-chain 3-ketoacyl-CoA synthase activity is a
vinorine synthase activity is a
transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer is a
transferase activity, transferring aldehyde or ketonic groups is a
transferase activity, transferring alkyl or aryl (other than methyl) groups is a
transferase activity, transferring glycosyl groups is a
transferase activity, transferring nitrogenous groups is a
transferase activity, transferring one-carbon groups is a
transferase activity, transferring phosphorus-containing groups is a
transferase activity, transferring selenium-containing groups is a
transferase activity, transferring sulfur-containing groups is a
UDP-L-rhamnose synthase activity is a
molecular transducer activity is a
nutrient reservoir activity is a
protein tag is a
small molecule sensor activity is a
structural molecule activity is a
transcription regulator activity is a
transporter activity is a