Gene ontology ID
GO:0036317
Definition
Catalysis of the hydrolysis of a 5' tyrosyl-RNA phosphodiester bond between a protein and RNA. In picornaviruses, this covalent bond connects VPg, a viral-encoded protein essential for RNA replication, to the 5' end of all nascent picornavirus genomes; it is cleaved from viral RNA prior to its engaging in protein synthesis
Synonyms
1. unlinkase activity
2. uridylylpolynucleotide-(5' P->O)- tyrosine phosphodiesterase activity
3. VPg unlinkase activity
4. Y-pUpN PDE activity
References
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at least 1 tissue/ enzyme/ localization link in this branch
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tissue/ enzyme/ localization link to BRENDA