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Version 2014-12-22
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Details for catechol O-methyltransferase activity
2.1.1.6
Gene ontology ID
GO:0016206
Definition
Catalysis of the reaction: S-adenosyl-L-methionine + a catechol = S-adenosyl-L-homocysteine + a guaiacol
Synonyms
1. catechol methyltransferase activity
2. catecholamine O-methyltransferase activity
3. COMT I
4. COMT II
5. MB-COMT (membrane-bound form of catechol-O-methyltransferase)
6. S-adenosyl-L-methionine:catechol O-methyltransferase activity
7. S-COMT (soluble form of catechol-O-methyltransferase)
References
1. EC 2.1.1.6
2. MetaCyc CATECHOL-O-METHYLTRANSFERASE-RXN
3. Reactome: R-HSA-175983 "COMT transfer CH3 from AdoMet to 3,4DHBNZ"
4. Reactome: R-HSA-8955010 "LRTOMT transfers methyl group from AdoMet to DA, forming 3MT"
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