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Gene ontology
Version 2014-12-22
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Details for archaeosine-tRNA biosynthetic process
Gene ontology ID
GO:0002927
Definition
The chemical reactions and pathways involved in the biosynthesis of archaeosine, an archaea-specific modified base found at position 15 in the D-loop of certain archaeal tRNAs
Comment
Archaeosine (7-formamidino-7-deazaguanosine) is a structural variant of the hypermodified nucleoside 7-deazaguanosine. The biosynthesis pathway starts with archaeosine tRNA-guanine transglycosylase (ArcTGT) which catalyzes the exchange of guanine at position 15 in the D-loop of archaeal tRNAs with a free 7-cyano-7-deazaguanine.
References
1. GOC: hjd
2. UniPathway: UPA00393
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