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Gene ontology
Version 2014-12-22
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Details for prostaglandin-I synthase activity
5.3.99.4
Gene ontology ID
GO:0008116
Definition
Catalysis of the reaction: prostaglandin H(2) = prostaglandin I(2)
Synonyms
1. (5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate 6-isomerase activity
2. cytochrome P450 CYP8A1
3. PGI(2) synthase activity
4. PGI(2) synthetase activity
5. PGI2 synthase activity
6. PGI2 synthetase activity
7. prostacyclin synthase activity
8. prostacycline synthetase activity
9. prostagladin I2 synthetase activity
References
1. EC 5.3.99.4
2. RHEA: 23580
3. KEGG REACTION: R02267
4. MetaCyc PROSTAGLANDIN-I-SYNTHASE-RXN
5. Reactome: R-HSA-76496 "PTGIS, CYP8A1 isomerise PGH2 to PGI2"
Legend
is an element of the parent element
is a part of the parent element
is related to the parent element
derives from the parent element
// at least 1 tissue/ enzyme/ localization link in this branch
// tissue/ enzyme/ localization link to BRENDA
Condensed Tree View
Gene ontology
molecular_function is a
catalytic activity is a
isomerase activity is a
intramolecular oxidoreductase activity is a
prostaglandin-I synthase activity is a
Tree view
Gene ontology
biological_process is a
cellular_component is a
molecular_function is a
binding is a
catalytic activity is a
catalytic activity, acting on a protein is a
catalytic activity, acting on DNA is a
catalytic activity, acting on RNA is a
cyclase activity is a
hydrolase activity is a
isomerase activity is a
(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity is a
4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase activity is a
cis-trans isomerase activity is a
dihydroneopterin triphosphate 2'-epimerase activity is a
eoxin A4 synthase activity is a
hepoxilin A3 synthase activity is a
hexulose-6-phosphate isomerase activity is a
intramolecular lyase activity is a
intramolecular oxidoreductase activity is a
2-carboxy-2-hydroxy-8-carboxychromene isomerase activity is a
2-hydroxy-7-hydroxymethylchromene-2-carboxylate isomerase activity is a
2-hydroxy-8-methylchromene-2-carboxylate isomerase activity is a
2-hydroxychromene-2-carboxylate isomerase activity is a
2-hydroxytetrahydrofuran isomerase activity is a
capsanthin synthase activity is a
capsorubin synthase activity is a
intramolecular oxidoreductase activity, interconverting aldoses and ketoses is a
intramolecular oxidoreductase activity, interconverting keto- and enol-groups is a
intramolecular oxidoreductase activity, transposing C=C bonds is a
5-carboxymethyl-2-hydroxymuconate delta-isomerase activity is a
aconitate delta-isomerase activity is a
ascopyrone tautomerase activity is a
C-8 sterol isomerase activity is a
cholestenol delta-isomerase activity is a
delta3,5-delta2,4-dienoyl-CoA isomerase activity is a
dodecenoyl-CoA delta-isomerase activity is a
dopachrome isomerase activity is a
isopentenyl-diphosphate delta-isomerase activity is a
isopiperitenone delta-isomerase activity is a
methylitaconate delta-isomerase activity is a
muconolactone delta-isomerase activity is a
polyenoic fatty acid isomerase activity is a
prostaglandin-A1 delta-isomerase activity is a
steroid delta-isomerase activity is a
trans-2,3-dihydro-3-hydroxy-anthranilate isomerase activity is a
trans-2-decenoyl-acyl-carrier-protein isomerase activity is a
vinylacetyl-CoA delta-isomerase activity is a
intramolecular oxidoreductase activity, transposing S-S bonds is a
lachrymatory factor synthase activity is a
neoxanthin synthase activity is a
prostaglandin-D synthase activity is a
prostaglandin-E synthase activity is a
prostaglandin-I synthase activity is a
styrene-oxide isomerase activity is a
thromboxane-A synthase activity is a
intramolecular transferase activity is a
N-acylmannosamine-6-phosphate 2-epimerase activity is a
peroxynitrite isomerase activity is a
racemase and epimerase activity is a
sulfoquinovose isomerase activity is a
thiocyanate isomerase activity is a
ligase activity is a
lyase activity is a
peptidoglycan muralytic activity is a
transferase activity is a
molecular transducer activity is a
nutrient reservoir activity is a
protein tag is a
small molecule sensor activity is a
structural molecule activity is a
transcription regulator activity is a
transporter activity is a