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Gene ontology
Version 2014-12-22
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Details for thromboxane-A synthase activity
5.3.99.5
Gene ontology ID
GO:0004796
Definition
Catalysis of the reaction: prostaglandin H(2) = thromboxane A(2)
Synonyms
1. (5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate isomerase activity
2. (5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate thromboxane-A2-isomerase activity
3. cytochrome P450 CYP5
4. thromboxane synthase activity
5. thromboxane synthetase activity
References
1. EC 5.3.99.5
2. RHEA: 17137
3. KEGG REACTION: R02268
4. MetaCyc THROMBOXANE-A-SYNTHASE-RXN
5. Reactome: R-HSA-5603275 "Defective TBXAS1 does not isomerise PGH2 to TXA2"
6. Reactome: R-HSA-76500 "TBXAS1 isomerises PGH2 to TXA2"
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