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Gene ontology
Version 2014-12-22
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Details for retromer, cargo-selective complex
Gene ontology ID
GO:0030906
Definition
The trimeric subcomplex of the retromer, believed to be closely associated with the membrane. This trimeric complex is responsible for recognizing and binding to cargo molecules. The complex comprises three Vps proteins in both yeast and mammalian cells: Vps35p, Vps29p, and Vps26p in yeast, and VPS35, VPS29 and VPS26A or VPS26B in mammals
Synonyms
1. cargo-selective retromer subcomplex
2. retromer complex, inner shell
3. retromer CSC
4. retromer, cargo recognition complex
5. retromer, CRC
References
1. GOC: bf
2. PMID 11102511
3. PMID 26220253
4. PMID 9700157
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