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Gene ontology
Version 2014-12-22
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Details for hypoxanthine phosphoribosyltransferase activity
2.4.2.8
Gene ontology ID
GO:0004422
Definition
Catalysis of the reaction: IMP + diphosphate = hypoxanthine + 5-phospho-alpha-D-ribose 1-diphosphate
Synonyms
1. 6-hydroxypurine phosphoribosyltransferase activity
2. 6-mercaptopurine phosphoribosyltransferase activity
3. guanine-hypoxanthine phosphoribosyltransferase activity
4. HGPRTase activity
5. HPRT
6. hypoxanthine-guanine phosphoribosyltransferase activity
7. IMP diphosphorylase activity
8. IMP pyrophosphorylase activity
9. IMP-GMP pyrophosphorylase activity
10. IMP:diphosphate phospho-D-ribosyltransferase activity
11. inosinate pyrophosphorylase activity
12. inosine 5'-phosphate pyrophosphorylase activity
13. inosinic acid pyrophosphorylase activity
14. inosinic pyrophosphorylase activity
15. purine-6-thiol phosphoribosyltransferase activity
16. Transphosphoribosidase activity
References
1. EC 2.4.2.8
2. GOC: curators
3. KEGG REACTION: R01132
4. MetaCyc HYPOXANPRIBOSYLTRAN-RXN
5. Reactome: R-HSA-74215 "guanine or hypoxanthine + PRPP => GMP or IMP + PPi (HPRT1)"
6. RHEA: 17973
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