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Version 2014-12-22
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Details for phenylalanine 4-monooxygenase activity
1.14.16.1
Gene ontology ID
GO:0004505
Definition
Catalysis of the reaction: L-phenylalanine + tetrahydrobiopterin + O2 = L-tyrosine + 4-alpha-hydroxytetrahydrobiopterin
Synonyms
1. L-phenylalanine,tetrahydrobiopterin:oxygen oxidoreductase (4-hydroxylating)
2. PAH activity
3. phenylalaninase activity
4. phenylalanine 4-hydroxylase activity
5. phenylalanine hydroxylase activity
References
1. EC 1.14.16.1
2. MetaCyc PHENYLALANINE-4-MONOOXYGENASE-RXN
3. Reactome: R-HSA-5649483 "Defective PAH does not hydroxylate L-Phe to L-Tyr"
4. Reactome: R-HSA-71118 "PAH tetramer hydroxylates L-Phe to L-Tyr"
5. RHEA: 20273
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