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BRENDA support

Ontology explorer

Gene ontology
Version 2014-12-22
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Details for epidermal growth factor catabolic process
Gene ontology ID
GO:0007174
Definition
The chemical reactions and pathways resulting in the breakdown of epidermal growth factor (EGF), following internalization of the receptor-bound ligand into the signal-receiving cell. Full breakdown of epidermal growth factor results in a ligand that is unable to bind and activate its receptor
Comment
This term describes the breakdown of epidermal growth factor within the cell, following internalization. For proteolysis events that result in the maturation of an epidermal growth factor receptor ligand, see 'epidermal growth factor receptor ligand maturation ; GO:'.
Synonyms
1. EGF breakdown
2. EGF catabolism
3. EGF receptor ligand processing
4. epidermal growth factor breakdown
5. epidermal growth factor catabolism
6. epidermal growth factor ligand processing
7. intracellular EGF processing
8. receptor-mediated EGF processing
References
1. GOC: bf
2. GOC: signaling
3. PMID 2985587
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