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Ontology explorer

Gene ontology
Version 2014-12-22
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Details for granulocyte-macrophage colony-stimulating factor signaling pathway
Gene ontology ID
GO:0038157
Definition
A series of molecular signals initiated by the binding of the cytokine granulocyte macrophage colony-stimulating factor (GM-CSF) to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. GM-CSF binds to a heterodimer receptor (CSF2R) consisting of an alpha ligand-binding subunit, and a common beta subunit that is shared with other cytokine receptors
Synonyms
1. CSF2 signaling pathway
2. GM-CSF receptor signaling pathway
3. GM-CSF signaling pathway
4. granulocyte-macrophage colony-stimulating factor receptor signaling pathway
5. granulocyte-macrophage colony-stimulating factor signalling pathway
References
1. GOC: nhn
2. GOC: signaling
3. PMID 17027509
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