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Gene ontology
Version 2014-12-22
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Details for positive regulation of blood-brain barrier permeability
Gene ontology ID
GO:1905605
Definition
Any process that increases blood-brain barrier permeability, the quality of the blood-brain barrier that allows for a controlled passage of substances (e.g. macromolecules, small molecules, ions) into and out of the brain
Synonyms
1. activation of maintenance of permeability of BBB
2. activation of maintenance of permeability of blood-brain barrier
3. positive regulation of BBB permeability
4. positive regulation of blood/brain barrier permeability
5. up-regulation of BBB permeability
6. up-regulation of blood-brain barrier permeability
7. up-regulation of blood/brain barrier permeability
8. upregulation of BBB permeability
9. upregulation of blood-brain barrier permeability
10. upregulation of blood/brain barrier permeability
References
1. GO REF: 0000058
2. GOC: als
3. GOC: aruk
4. GOC: bc
5. GOC: TermGenie
6. PMID 22524708
7. PMID 30280653
Legend
is an element of the parent element
is a part of the parent element
is related to the parent element
derives from the parent element
// at least 1 tissue/ enzyme/ localization link in this branch
// tissue/ enzyme/ localization link to BRENDA
Condensed Tree View
Gene ontology
biological_process is a
biological regulation is a
negative regulation of natural killer cell differentiation is a
negative regulation of natural killer cell differentiation involved in immune response is a
positive regulation of neutrophil activation is a
positive regulation of thrombin-activated receptor signaling pathway is a
positive regulation of histone H3-K9 dimethylation is a
DNM1L-mediated stimulation of mitophagy in response to mitochondrial depolarization is a
regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization
positive regulation of synapse pruning is a
positive regulation of tight junction disassembly is a
regulation of biological quality is a
homeostatic process is a
anatomical structure homeostasis is a
tissue homeostasis is a
maintenance of blood-brain barrier is a
regulation of blood-brain barrier permeability part of
positive regulation of blood-brain barrier permeability is a
sinoatrial valve morphogenesis is a
female gonad development is a
endocardium development part of
modification by organism of cell wall of other organism involved in symbiotic interaction is a
modulation by symbiont of host process is a
peg and socket contact is a
inner dense plaque of desmosome part of
calpain complex part of
carbamoyl-phosphate synthase complex part of
transcription export complex 2 part of
transcription factor TFIIH core complex part of
CCR4-NOT core complex part of
Tree view
Gene ontology
biological_process is a
behavior is a
biological adhesion is a
biological phase is a
biological regulation is a
negative regulation of phosphatidylcholine metabolic process is a
regulation of biological process is a
modulation of host virulence by virus is a
negative regulation of biological process is a
negative regulation of natural killer cell differentiation involved in immune response is a
positive regulation of biological process is a
positive regulation by symbiont of entry into host is a
positive regulation of action potential is a
positive regulation of asexual reproduction is a
positive regulation of biomineralization is a
positive regulation of cellular process is a
positive regulation of actin filament severing is a
positive regulation of amino acid uptake involved in synaptic transmission is a
positive regulation of calcium ion transport into cytosol is a
positive regulation of cartilage condensation is a
positive regulation of catecholamine uptake involved in synaptic transmission is a
positive regulation of cell activation is a
positive regulation of neutrophil degranulation is a
positive regulation of cell adhesion molecule production is a
positive regulation of cell aging is a
positive regulation of cell communication is a
positive regulation of cell cycle is a
positive regulation of cell cycle process is a
positive regulation of attachment of spindle microtubules to kinetochore is a
positive regulation of cell cycle phase transition is a
positive regulation of centrosome cycle is a
positive regulation of chromosome separation is a
positive regulation of cytokinesis is a
positive regulation of DNA endoreduplication is a
positive regulation of G0 to G1 transition is a
positive regulation of G1 to G0 transition is a
positive regulation of meiotic cell cycle process involved in oocyte maturation is a
positive regulation of meiotic DNA double-strand break formation is a
positive regulation of meiotic nuclear division is a
positive regulation of mitotic nuclear division is a
positive regulation of mitotic nuclear envelope disassembly is a
positive regulation of mitotic spindle organization is a
positive regulation of nuclear cell cycle DNA replication is a
positive regulation of protein localization to meiotic spindle pole body is a
positive regulation of sexual sporulation resulting in formation of a cellular spore is a
positive regulation of sister chromatid cohesion is a
positive regulation of spindle assembly is a
positive regulation of cyclin-dependent protein serine/threonine kinase activity is a
positive regulation of meiotic cell cycle is a
positive regulation of mitotic cell cycle is a
positive regulation of cell death is a
positive regulation of cell differentiation is a
positive regulation of cell division is a
positive regulation of cell growth is a
positive regulation of cell killing is a
positive regulation of cell population proliferation is a
positive regulation of cell wall organization or biogenesis is a
positive regulation of cellular component biogenesis is a
positive regulation of cellular component movement is a
positive regulation of cellular component organization is a
positive regulation of adherens junction organization is a
positive regulation of blood microparticle formation is a
positive regulation of capsule organization is a
positive regulation of cell projection organization is a
positive regulation of cell-substrate junction organization is a
positive regulation of chylomicron remodeling is a
positive regulation of endocytosis is a
positive regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation is a
positive regulation of extracellular matrix organization is a
positive regulation of integrin biosynthetic process is a
positive regulation of membrane invagination is a
positive regulation of membrane tubulation is a
positive regulation of neuromuscular junction development is a
positive regulation of organelle organization is a
positive regulation of autophagosome maturation is a
positive regulation of chloroplast fission is a
positive regulation of chromosome organization is a
positive regulation of chromatin organization is a
positive regulation of chromosome condensation is a
positive regulation of DNA duplex unwinding is a
positive regulation of G-quadruplex DNA unwinding is a
positive regulation of telomere maintenance is a
positive regulation of telomere capping is a
positive regulation of telomere maintenance in response to DNA damage is a
positive regulation of telomere maintenance via recombination is a
positive regulation of telomere maintenance via telomere lengthening is a
positive regulation of telomeric loop disassembly is a
positive regulation of telomeric D-loop disassembly is a
positive regulation of telomeric loop formation is a
positive regulation of cytoskeleton organization is a
positive regulation of endoplasmic reticulum tubular network organization is a
positive regulation of endosome organization is a
positive regulation of melanosome organization is a
positive regulation of mitochondrion organization is a
positive regulation of nuclear division is a
positive regulation of peroxisome organization is a
positive regulation of phagosome maturation is a
positive regulation of postsynaptic density organization is a
positive regulation of secretory granule organization is a
positive regulation of synaptic vesicle lumen acidification is a
positive regulation of vacuole organization is a
positive regulation of vesicle fusion is a
positive regulation of phospholipid translocation is a
positive regulation of plasma membrane raft polarization is a
positive regulation of plasma membrane repair is a
positive regulation of postsynaptic membrane organization is a
positive regulation of presynaptic membrane organization is a
positive regulation of protein-containing complex disassembly is a
positive regulation of supramolecular fiber organization is a
positive regulation of synapse maturation is a
positive regulation of synapse pruning is a
positive regulation of synapse structural plasticity is a
positive regulation of synaptic vesicle membrane organization is a
positive regulation of syncytium formation by plasma membrane fusion is a
positive regulation of terminal button organization is a
positive regulation of tight junction disassembly is a
positive regulation of very-low-density lipoprotein particle remodeling is a
positive regulation of vitellogenesis is a
positive regulation of cellular metabolic process is a
positive regulation of cellular pH reduction is a
positive regulation of cellular protein localization is a
positive regulation of cellular response to alcohol is a
positive regulation of cellular response to drug is a
positive regulation of cellular response to gamma radiation is a
positive regulation of cellular response to heat is a
positive regulation of cellular response to hepatocyte growth factor stimulus is a
positive regulation of cellular response to hypoxia is a
positive regulation of cellular response to insulin stimulus is a
positive regulation of cellular response to macrophage colony-stimulating factor stimulus is a
positive regulation of cellular response to manganese ion is a
positive regulation of cellular response to oxidative stress is a
positive regulation of cellular response to oxidopamine is a
positive regulation of cellular response to thapsigargin is a
positive regulation of cellular response to transforming growth factor beta stimulus is a
positive regulation of cellular response to tunicamycin is a
positive regulation of cellular response to very-low-density lipoprotein particle stimulus is a
positive regulation of cellular response to X-ray is a
positive regulation of chromosome segregation is a
positive regulation of conjugation is a
positive regulation of cytolysis is a
positive regulation of establishment of bipolar cell polarity is a
positive regulation of establishment or maintenance of cell polarity regulating cell shape is a
positive regulation of horizontal cell localization is a
positive regulation of intracellular mRNA localization is a
positive regulation of intracellular transport is a
positive regulation of melanosome transport is a
positive regulation of myelination is a
positive regulation of peroxidase activity is a
positive regulation of phagocytosis is a
positive regulation of phenotypic switching is a
positive regulation of protein folding is a
positive regulation of response to cell cycle checkpoint signaling is a
positive regulation of response to DNA damage stimulus is a
positive regulation of response to endoplasmic reticulum stress is a
positive regulation of ribonucleoprotein complex localization is a
positive regulation of secretion by cell is a
positive regulation of sequestering of calcium ion is a
positive regulation of sequestering of zinc ion is a
positive regulation of serotonin uptake is a
positive regulation of single-species biofilm formation is a
positive regulation of stomatal opening is a
positive regulation of synaptic vesicle clustering is a
positive regulation of synaptic vesicle recycling is a
positive regulation of synaptic vesicle transport is a
positive regulation of transcytosis is a
positive regulation of transmembrane transport is a
positive regulation of transposition is a
positive regulation of vacuolar transport is a
positive regulation of vesicle docking is a
positive regulation of circadian rhythm is a
positive regulation of developmental pigmentation is a
positive regulation of developmental process is a
positive regulation of DNA-binding transcription factor activity is a
positive regulation of dosage compensation by inactivation of X chromosome is a
positive regulation of establishment of protein localization is a
positive regulation of establishment of RNA localization to telomere is a
positive regulation of growth is a
positive regulation of guanyl-nucleotide exchange factor activity is a
positive regulation of hemostasis is a
positive regulation of immune system process is a
positive regulation of lipid localization is a
positive regulation of locomotion is a
positive regulation of membrane depolarization is a
positive regulation of membrane hyperpolarization is a
positive regulation of metabolic process is a
positive regulation of mRNA alternative polyadenylation is a
positive regulation of multi-organism process is a
positive regulation of multicellular organismal process is a
positive regulation of nitrogen utilization is a
positive regulation of phosphorus utilization is a
positive regulation of posttranscriptional gene silencing is a
positive regulation of protein localization to cell-cell junction is a
positive regulation of protein localization to synapse is a
positive regulation of reproductive process is a
positive regulation of response to stimulus is a
positive regulation of short-term synaptic potentiation is a
positive regulation of signaling is a
positive regulation of sulfur utilization is a
positive regulation of telomerase RNA localization to Cajal body is a
positive regulation of transport is a
positive regulation of viral process is a
regulation of action potential is a
regulation of asexual reproduction is a
regulation of biomineralization is a
regulation of carbohydrate utilization is a
regulation of carbon utilization is a
regulation of cellular process is a
regulation of circadian rhythm is a
regulation of developmental pigmentation is a
regulation of developmental process is a
regulation of estrogen receptor binding is a
regulation of growth is a
regulation of guanyl-nucleotide exchange factor activity is a
regulation of hemostasis is a
regulation of immune system process is a
regulation of interspecies interactions between organisms is a
regulation of localization is a
regulation of locomotion is a
regulation of membrane hyperpolarization is a
regulation of metabolic process is a
regulation of multi-organism process is a
regulation of multicellular organismal process is a
regulation of nitrogen utilization is a
regulation of phosphorus utilization is a
regulation of plasma lipoprotein particle levels is a
regulation of reproductive process is a
regulation of response to stimulus is a
regulation of signaling is a
regulation of sulfur utilization is a
regulation of biological quality is a
homeostatic process is a
anatomical structure homeostasis is a
germ-line stem-cell niche homeostasis is a
muscle cell cellular homeostasis is a
neuron cellular homeostasis is a
telomere maintenance is a
tissue homeostasis is a
amnioserosa maintenance is a
bone resorption is a
cartilage homeostasis is a
chemical homeostasis within a tissue is a
compartment boundary maintenance is a
epithelial structure maintenance is a
homeostasis of number of cells within a tissue is a
maintenance of blood-brain barrier is a
regulation of blood-brain barrier permeability part of
negative regulation of blood-brain barrier permeability is a
positive regulation of blood-brain barrier permeability is a
maintenance of lens transparency is a
retina homeostasis is a
B cell homeostatic proliferation part of
cellular homeostasis is a
chemical homeostasis is a
homeostasis of number of cells is a
multicellular organismal homeostasis is a
regulation of liquid surface tension is a
maintenance of location is a
modulation of age-related behavioral decline is a
regulation of anatomical structure size is a
regulation of appetite is a
regulation of blood pressure is a
regulation of body fluid levels is a
regulation of brood size is a
regulation of buoyancy is a
regulation of circulating fibrinogen levels is a
regulation of DNA stability is a
regulation of hormone levels is a
regulation of membrane lipid distribution is a
regulation of membrane permeability is a
regulation of membrane potential is a
regulation of neurotransmitter levels is a
regulation of nucleosome density is a
regulation of postsynaptic membrane neurotransmitter receptor levels is a
regulation of protein complex stability is a
regulation of protein stability is a
regulation of R8 cell spacing in compound eye is a
regulation of synapse structure or activity is a
regulation of translational fidelity is a
regulation of tube architecture, open tracheal system is a
regulation of vascular permeability is a
regulation of molecular function is a
biomineralization is a
carbohydrate utilization is a
carbon utilization is a
cellular process is a
detoxification is a
developmental process is a
luteinization part of
luteolysis part of
ovarian follicle development part of
ovulation from ovarian follicle part of
endocardial endothelium development part of
growth is a
immune system process is a
interspecies interaction between organisms is a
disruption by organism of cell wall of other organism involved in symbiotic interaction is a
induction by symbiont of tumor or growth in host is a
modulation by symbiont of host defense response is a
modulation by symbiont of host hormone or growth regulator levels is a
modulation by symbiont of nutrient release from host is a
modulation by symbiont of RNA levels in host is a
modulation by virus of host process is a
intraspecies interaction between organisms is a
localization is a
establishment of localization is a
establishment of protein localization is a
establishment of RNA localization is a
transport is a
cofactor transport is a
drug transport is a
extracellular transport is a
eye pigment precursor transport is a
fatty-acyl group transport is a
fluid transport is a
gas transport is a
import into cell is a
intestinal absorption is a
ion transport is a
mitochondrial transport is a
multi-organism transport is a
neurotransmitter transport is a
nitrogen compound transport is a
2-aminoethylphosphonate transport is a
acridine transport is a
amide transport is a
ceramide transport is a
peptide transport is a
urea transport is a
amine transport is a
aminotriazole transport is a
modified amino acid transport is a
monoamine transport is a
nitrogen utilization
nucleobase transport is a
nucleobase-containing compound transport is a
peptidoglycan transport is a
polyamine transport is a
triazole transport is a
organic substance transport is a
secretion is a
sulfur compound transport is a
toxin transport is a
transepithelial transport is a
vascular transport is a
vitamin transport is a
xenobiotic transport is a
macromolecule localization is a
multi-organism localization is a
locomotion is a
metabolic process is a
multi-organism process is a
multicellular organismal process is a
pigmentation is a
reproduction is a
response to stimulus is a
rhythmic process is a
signaling is a
cellular_component is a
cell is a
cellular anatomical entity is a
A band is a696 BRENDA localization in branch, click for list of all
acroblast is a
acrosomal matrix is a693 BRENDA localization in branch, click for list of all
actin body is a
actin cap is a692 BRENDA localization in branch, click for list of all
actin filament branch point is a
actin filament bundle is a
actin fusion focus is a
actin wave is a
actomyosin is a686 BRENDA localization in branch, click for list of all
actomyosin contractile ring, distal actin filament layer is a
actomyosin contractile ring, intermediate layer is a
actomyosin contractile ring, proximal layer is a
alae of collagen and cuticulin-based cuticle extracellular matrix is a
annular furrow extracellular matrix is a
annuli extracellular matrix is a
apical complex is a685 BRENDA localization in branch, click for list of all
apical cytoplasm is a
apical lamina of hyaline layer is a
apical part of cell is a680 BRENDA localization in branch, click for list of all
ascus epiplasm is a
assemblon is a
axon collateral is a678 BRENDA localization in branch, click for list of all
axon hillock is a677 BRENDA localization in branch, click for list of all
axon initial segment is a676 BRENDA localization in branch, click for list of all
axonemal basal plate is a
axonemal central apparatus is a
axonemal outer doublet is a
axoneme is a671 BRENDA localization in branch, click for list of all
bacterial biofilm matrix surface is a
bacterial-type flagellum basal body is a
bacterial-type flagellum filament is a
bacterial-type flagellum hook is a
bacterial-type flagellum hook-filament junction is a
basal labyrinth is a
basal layer of collagen and cuticulin-based cuticle extracellular matrix is a
basal part of cell is a
basolateral cytoplasm is a
bilobe structure is a
blood microparticle is a
Casparian strip is a
cell body is a666 BRENDA localization in branch, click for list of all
cell division site is a663 BRENDA localization in branch, click for list of all
cell junction is a658 BRENDA localization in branch, click for list of all
cell leading edge is a
cell periphery is a621 BRENDA localization in branch, click for list of all
cell plate is a452 BRENDA localization in branch, click for list of all
cell pole is a451 BRENDA localization in branch, click for list of all
cell projection is a
cell septum is a444 BRENDA localization in branch, click for list of all
cell surface is a443 BRENDA localization in branch, click for list of all
cell tip is a
growing cell tip is a
new growing cell tip is a
old growing cell tip is a
hyphal tip is a
non-growing cell tip is a
cell trailing edge is a
cellular bud is a
central element is a441 BRENDA localization in branch, click for list of all
central plaque of spindle pole body is a
centriolar satellite is a
centrosomal corona is a
chiasma is a440 BRENDA localization in branch, click for list of all
chromatin is a439 BRENDA localization in branch, click for list of all
chromosomal region is a422 BRENDA localization in branch, click for list of all
cnida is a
compact myelin is a416 BRENDA localization in branch, click for list of all
concave side of sperm head is a
cone matrix sheath is a
contractile ring is a415 BRENDA localization in branch, click for list of all
cortical layer of collagen and cuticulin-based cuticle extracellular matrix is a
costamere is a
cytoophidium is a414 BRENDA localization in branch, click for list of all
cytoplasm is a413 BRENDA localization in branch, click for list of all
deep fiber is a
dense fibrillar component is a233 BRENDA localization in branch, click for list of all
dense nuclear body is a
dinoflagellate antapex is a
dinoflagellate apex is a
dinoflagellate epicone is a
dinoflagellate hypocone is a
DNA replication termination region is a
eisosome is a232 BRENDA localization in branch, click for list of all
endonuclear canal is a231 BRENDA localization in branch, click for list of all
endospore core is a
ensheathing process is a
envelope is a230 BRENDA localization in branch, click for list of all
epicuticle of collagen and cuticulin-based cuticle extracellular matrix is a
extracellular matrix is a229 BRENDA localization in branch, click for list of all
extracellular region is a214 BRENDA localization in branch, click for list of all
extrachromosomal circular DNA is a197 BRENDA localization in branch, click for list of all
extrachromosomal DNA is a196 BRENDA localization in branch, click for list of all
extrinsic component of membrane is a
fibrillar center is a
Flemming body is a
gas vesicle shell is a
germ tube is a194 BRENDA localization in branch, click for list of all
granular component is a193 BRENDA localization in branch, click for list of all
half bridge of spindle pole body is a
host cellular component is a
incipient cellular bud site is a
inclusion body is a178 BRENDA localization in branch, click for list of all
inner membrane pellicle complex is a
inner plaque of spindle pole body is a
intermediate layer of spindle pole body is a
intracellular immature spore is a
intrinsic component of membrane is a
investment cone is a
lateral element is a
lateral loop is a
lateral part of cell is a
leaflet of membrane bilayer is a
manchette is a168 BRENDA localization in branch, click for list of all
median body is a
membrane is a167 BRENDA localization in branch, click for list of all
membrane-enclosed lumen is a
metaphase plate is a108 BRENDA localization in branch, click for list of all
microtubule bundle is a
microtubule end is a107 BRENDA localization in branch, click for list of all
microtubule organizing center is a105 BRENDA localization in branch, click for list of all
midbody is a99 BRENDA localization in branch, click for list of all
myelin sheath is a98 BRENDA localization in branch, click for list of all
neck portion of tanycyte is a
nucleoid is a97 BRENDA localization in branch, click for list of all
nucleus lagging edge is a
nucleus leading edge is a
oral apparatus is a95 BRENDA localization in branch, click for list of all
organelle is a94 BRENDA localization in branch, click for list of all
intracellular organelle is a83 BRENDA localization in branch, click for list of all
eyespot apparatus is a
intracellular membrane-bounded organelle is a
intracellular non-membrane-bounded organelle is a
aster is a56 BRENDA localization in branch, click for list of all
bacterial thylakoid is a
blepharoplast is a
chlorosome is a55 BRENDA localization in branch, click for list of all
chromosome is a54 BRENDA localization in branch, click for list of all
contractile vacuole complex is a37 BRENDA localization in branch, click for list of all
cytoskeleton is a36 BRENDA localization in branch, click for list of all
deuterosome is a
gas vesicle is a7 BRENDA localization in branch, click for list of all
lipid droplet is a6 BRENDA localization in branch, click for list of all
polyhedral organelle is a
protein aggregate center is a
ribonucleoprotein granule is a
ribosome is a4 BRENDA localization in branch, click for list of all
synaptic ribbon is a
transmembrane actin-associated (TAN) line is a
intracellular vesicle is a
organelle subcompartment part of
organelle-enclosing lipid monolayer part of
zeta DNA polymerase complex part of
magnetosome is a1 BRENDA localization in branch, click for list of all
membrane-bounded organelle is a
non-membrane-bounded organelle is a
organelle membrane contact site part of
pellicle is a9 BRENDA localization in branch, click for list of all
periplasmic space is a8 BRENDA localization in branch, click for list of all
photoreceptor inner segment is a7 BRENDA localization in branch, click for list of all
polar tube is a6 BRENDA localization in branch, click for list of all
site of polarized growth is a
somatodendritic compartment is a
sperm head is a5 BRENDA localization in branch, click for list of all
sperm head-tail coupling apparatus is a
sporoplasm is a
subapical part of cell is a
supramolecular complex is a4 BRENDA localization in branch, click for list of all
symplast is a3 BRENDA localization in branch, click for list of all
tail portion of tanycyte is a
thylakoid is a2 BRENDA localization in branch, click for list of all
Yb body is a
intracellular is a73 BRENDA localization in branch, click for list of all
other organism part is a
protein-containing complex is a50 BRENDA localization in branch, click for list of all
virion is a9 BRENDA localization in branch, click for list of all
molecular_function is a