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Gene ontology
Version 2014-12-22
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Details for signaling adaptor activity
Gene ontology ID
GO:0035591
Definition
The binding activity of a molecule that brings together two or more molecules in a signaling pathway, permitting those molecules to function in a coordinated way. Adaptor molecules themselves do not have catalytic activity
Comment
A signaling adaptor can bring together both protein and non-protein molecules within a signaling pathway. Scaffold proteins act in at least four ways: tethering signaling components, localizing these components to specific areas of the cell, regulating signal transduction by coordinating positive and negative feedback signals, and insulating correct signaling proteins from competing proteins (PMID:19104498).
Synonyms
1. signaling scaffold activity
2. signalling adaptor activity
References
1. GOC: bf
2. PMID 19104498
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is an element of the parent element
is a part of the parent element
is related to the parent element
derives from the parent element
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