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Gene ontology
Version 2014-12-22
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Details for serpin family protein binding
Gene ontology ID
GO:0097655
Definition
Interacting selectively and non-covalently with any member of the serpin protein family (serine protease inhibitors or classified inhibitor family I4). Serpins are a broadly distributed family of protease inhibitors that use a conformational change to inhibit target enzymes. They are central in controlling many important proteolytic cascades. The majority of serpins inhibit serine proteases, but serpins that inhibit caspases and papain-like cysteine proteases have also been identified. Rarely, serpins perform a non-inhibitory function; for example, several human serpins function as hormone transporters and certain serpins function as molecular chaperones or tumor suppressors
Synonyms
1. SERPIN family protein binding
References
1. GOC: mr
2. InterPro: IPR000215
3. PMID 16737556
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is a part of the parent element
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derives from the parent element
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