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Ontology explorer

Gene ontology
Version 2014-12-22
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Details for immunological synapse formation
Gene ontology ID
GO:0001771
Definition
The formation of an area of close contact between a lymphocyte (T-, B-, or natural killer cell) and a target cell through the clustering of particular signaling and adhesion molecules and their associated membrane rafts on both the lymphocyte and target cell, which facilitates activation of the lymphocyte, transfer of membrane from the target cell to the lymphocyte, and in some situations killing of the target cell through release of secretory granules and/or death-pathway ligand-receptor interaction
Synonyms
1. formation of immunological synapse
References
1. GOC: mgi curators
2. PMID 11244041
3. PMID 11376330
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derives from the parent element
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