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Gene ontology
Version 2014-12-22
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Details for CCR4-NOT complex
CCR4-NOT complex
Gene ontology ID
GO:0030014
Definition
The Ccr4-Not complex is an eukaryotically conserved deadenylase that can initiate cytoplasmic mRNA decay, and reduce translation by releasing poly(A)-binding protein (Pab1/PABPC1). Ccr4-Not contains seven core subunits, including two poly(A)-specific exonucleases, Ccr4/CNOT6/CNOT6L and Caf1/Pop2/CNOT7/CNOT8
References
1. GOC: sart
2. PMID 11113136
3. PMID 11239395
4. PMID 22785621
5. PMID 30601114
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