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Version 2014-12-22
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Details for DNA polymerase III complex
DNA polymerase III complex
Gene ontology ID
GO:0009360
Definition
The DNA polymerase III holoenzyme is a complex that contains 10 different types of subunits. These subunits are organized into 3 functionally essential sub-assemblies: the pol III core, the beta sliding clamp processivity factor and the clamp-loading complex. The pol III core carries out the polymerase and the 3'-5' exonuclease proofreading activities. The polymerase is tethered to the template via the sliding clamp processivity factor. The clamp-loading complex assembles the beta processivity factor onto the primer template and plays a central role in the organization and communication at the replication fork
Synonyms
1. DNA polymerase III holoenzyme complex
References
1. PMID 11525729
2. PMID 12940977
3. UniProt: P06710
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