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Gene ontology
Version 2014-12-22
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Details for heterotrimeric G-protein complex
heterotrimeric G-protein complex
Gene ontology ID
GO:0005834
Definition
Any of a family of heterotrimeric GTP-binding and hydrolyzing proteins; they belong to a superfamily of GTPases that includes monomeric proteins such as EF-Tu and RAS. Heterotrimeric G-proteins consist of three subunits; the alpha subunit contains the guanine nucleotide binding site and possesses GTPase activity; the beta and gamma subunits are tightly associated and function as a beta-gamma heterodimer; extrinsic plasma membrane proteins (cytoplasmic face) that function as a complex to transduce signals from G-protein coupled receptors to an effector protein
Comment
See also the molecular function term 'G-protein coupled receptor activity ; GO:0004930'.
References
1. ISBN 0198547684
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