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Gene ontology
Version 2014-12-22
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Details for eif4e-cup complex
Gene ontology ID
GO:1990500
Definition
A protein complex that causes translational repression in Drosophila. Prevents assembly of ribosomes at the mRNA by interfacing with a sequence-specific RNA-binding protein leading to recruitment of the CCR4 complex and consequently, reduction of the mRNA's poly(A) tail length. The complex is also required for dorso-ventral pattern formation in the embryo
Comment
An example of this is Eif4e in drome (P48598) in PMID:14723848 (inferred from physical interaction).
References
1. GOC: bhm
2. IntAct: EBI-9674930
3. PMID 14723848
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