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Version 2014-12-22
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Details for 3-methylcrotonyl-CoA carboxylase complex, mitochondrial
Gene ontology ID
GO:0002169
Definition
A mitochondrial protein complex which is capable of 3-methylcrotonyl-CoA carboxylase activity. In mammals, at least, consists as a dodecamer of 6 alpha and 6 beta subunits. MCCC-alpha has a covalently bound biotin essential for the ATP-dependent carboxylation. MCCC-beta possesses carboxyltransferase activity which presumably is essential for binding to 3-methylcrotonyl-CoA
Synonyms
1. mitochondrial 3-methylcrotonyl-CoA carboxylase holoenzyme
2. mitochondrial MCCC complex
3. mitochondrial methylcrotonoyl-CoA carboxylase complex
References
1. GOC: bf
2. GOC: hjd
3. PMID 15868465
4. PMID 17360195
5. PMID 22869039
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