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Literature summary extracted from

  • Seely, J.E.; Marshall, F.D.
    Carnosine-synthetase inhibition by beta-alanine analogues (1982), Life Sci., 30, 1763-1768.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
6.3.2.11 2-Aminoethylphosphonic acid weak Gallus gallus
6.3.2.11 2-Aminoethylphosphonic acid weak Rattus norvegicus
6.3.2.11 3-Aminopropane sulfonic acid competitive with respect to beta-Ala Gallus gallus
6.3.2.11 3-Aminopropane sulfonic acid competitive with respect to beta-Ala Rattus norvegicus
6.3.2.11 3-Aminopropanephosphonic acid
-
 Rattus norvegicus
6.3.2.11 5-Aminopentanoate no inhibition Gallus gallus
6.3.2.11 5-Aminopentanoate
-
 Rattus norvegicus
6.3.2.11 Aminooxyacetate
-
 Rattus norvegicus
6.3.2.11 Nipecotic acid
-
 Rattus norvegicus
6.3.2.11 O-Phosphoethanolamine weak Gallus gallus
6.3.2.11 O-Phosphoethanolamine weak Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
6.3.2.11 Gallus gallus
-
-
-
6.3.2.11 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
6.3.2.11 brain
-
 Gallus gallus
-
6.3.2.11 brain
-
 Rattus norvegicus
-
6.3.2.11 heart
-
 Gallus gallus
-
6.3.2.11 heart
-
 Rattus norvegicus
-
6.3.2.11 muscle skeletal Gallus gallus
-
6.3.2.11 muscle skeletal Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.3.2.11 ATP + L-His + beta-Ala
-
 Gallus gallus ADP + phosphate + carnosine
-
 ?
6.3.2.11 ATP + L-His + beta-Ala
-
 Rattus norvegicus ADP + phosphate + carnosine
-
 ?