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Literature summary extracted from

  • Wooley, D.E.; Tucker, J.S.; Green, G.; Evanson, J.M.
    A neutral collagenase from human gastric mucosa (1976), Biochem. J., 153, 119-126.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.24.7 1,10-phenanthroline
-
 Homo sapiens
3.4.24.7 alpha2-Macroglobulin
-
 Homo sapiens
3.4.24.7 Cys
-
 Homo sapiens
3.4.24.7 dithiothreitol
-
 Homo sapiens
3.4.24.7 EDTA
-
 Homo sapiens

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.4.24.7 38000
-
 gel filtration Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
3.4.24.7 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.24.7 gastric mucosa
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.24.7 Collagen + H2O
-
 Homo sapiens ? two collagen fragments representing 77% and 23% respectively of the length of the collagen molecule ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.4.24.7 7.5 8.5
-
 Homo sapiens

pH Range

EC Number pH Minimum pH Maximum Comment Organism
3.4.24.7 6.5 9.5 pH 6.5: about 65% of maximal activity, pH 9.5: about 60% of maximal activity Homo sapiens