Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Wong, B.; Murray, J.S.; Castellanos, M.; Croen, K.D.
    D-Arabitol metabolism in Candida albicans: studies of the biosynthetic pathway and the gene that encodes NAD-dependent D-arabitol dehydrogenase (1993), J. Bacteriol., 175, 6314-6320.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.1.1.11 gene over-expressed in S. cerevisiae BWG 1-7A and in Escherichia coli JM109, DH5-alpha Candida albicans
1.1.1.250 expression in Escherichia coli and Saccharomyces cerevisiae Candida albicans

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.1.1.11 30643
-
 x * 30643, calculated from gene sequence Candida albicans

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.11 D-arabinitol + NAD+ Candida albicans
-
 D-ribulose + NADH + H+
-
 ?
1.1.1.11 D-arabinitol + NAD+ Candida albicans B331
-
 D-ribulose + NADH + H+
-
 ?
1.1.1.250 D-ribulose + NADH Candida albicans catalyzes the final step in the synthesis of D-arabinitol D-arabinitol + NAD+
-
 ?
1.1.1.250 D-ribulose + NADH Candida albicans B331 catalyzes the final step in the synthesis of D-arabinitol D-arabinitol + NAD+
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.11 Candida albicans
-
 and strains WO-1, 1006, 1001
-
1.1.1.11 Candida albicans B331
-
 and strains WO-1, 1006, 1001
-
1.1.1.250 Candida albicans
-
-
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.1.1.11 0.17
-
 lysates of Escherichia coli, transformed with enzyme gene Candida albicans
1.1.1.11 0.37
-
 lysates of Saccharomyces cerevisiae, transformed with enzyme gene Candida albicans

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.11 D-arabinitol + NAD+
-
 Candida albicans D-ribulose + NADH + H+
-
 ?
1.1.1.11 D-arabinitol + NAD+
-
 Candida albicans B331 D-ribulose + NADH + H+
-
 ?
1.1.1.250 D-arabinitol + NAD+
-
 Candida albicans D-ribulose + NADH + H+
-
 ?
1.1.1.250 D-arabinitol + NAD+
-
 Candida albicans B331 D-ribulose + NADH + H+
-
 ?
1.1.1.250 D-ribulose + NADH catalyzes the final step in the synthesis of D-arabinitol Candida albicans D-arabinitol + NAD+
-
 ?
1.1.1.250 D-ribulose + NADH catalyzes the final step in the synthesis of D-arabinitol Candida albicans B331 D-arabinitol + NAD+
-
 ?

Subunits

EC Number Subunits Comment Organism
1.1.1.11 ? x * 30643, calculated from gene sequence Candida albicans

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.250 NAD+
-
 Candida albicans
1.1.1.250 NADH
-
 Candida albicans