EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
3.4.21.34 | Aprotinin | - |
Homo sapiens | |
3.4.21.34 | leupeptin | - |
Homo sapiens | |
3.4.21.34 | Pro-Phe-Arg-CH2Cl | - |
Homo sapiens | |
3.4.21.34 | Soybean trypsin inhibitor | - |
Homo sapiens |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
3.4.21.34 | cytosol | - |
Homo sapiens | 5829 | - |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
3.4.21.34 | 22000 | - |
1 * 36000, 1 * 28000, 1 * 22000, SDS-PAGE with reduction, 3 chains | Homo sapiens |
3.4.21.34 | 28000 | - |
1 * 36000, 1 * 28000, 1 * 22000, SDS-PAGE with reduction, 3 chains | Homo sapiens |
3.4.21.34 | 36000 | - |
1 * 36000, 1 * 28000, 1 * 22000, SDS-PAGE with reduction, 3 chains | Homo sapiens |
3.4.21.34 | 86000 | - |
? * 86000, SDS-PAGE, kallikrein II | Homo sapiens |
3.4.21.34 | 88000 | - |
? * 88000, SDS-PAGE, kallikrein I | Homo sapiens |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.4.21.34 | kininogen + H2O | Homo sapiens | cleaves Lys-Arg and Arg-Ser bonds in kininogen to produce bradykinin, participates in early phase of intrinsic blood coagulation | ? | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.4.21.34 | Homo sapiens | - |
kallikrein I, kallikrein II | - |
EC Number | Purification (Comment) | Organism |
---|---|---|
3.4.21.34 | - |
Homo sapiens |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
3.4.21.34 | plasma | - |
Homo sapiens | - |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
3.4.21.34 | additional information | - |
- |
Homo sapiens |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.4.21.34 | kininogen + H2O | cleaves Lys-Arg and Arg-Ser bonds in kininogen to produce bradykinin, participates in early phase of intrinsic blood coagulation | Homo sapiens | ? | - |
? | |
3.4.21.34 | Nalpha-Benzoyl-L-Arg ethyl ester + H2O | - |
Homo sapiens | Nalpha-Benzoyl-L-Arg + ethanol | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
3.4.21.34 | More | ? * 86000, SDS-PAGE, kallikrein II | Homo sapiens |
3.4.21.34 | More | ? * 88000, SDS-PAGE, kallikrein I | Homo sapiens |
3.4.21.34 | trimer | 1 * 36000, 1 * 28000, 1 * 22000, SDS-PAGE with reduction, 3 chains | Homo sapiens |