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Literature summary extracted from
- Human acylpeptide hydrolase. Studies on its thiol groups and mechanism of action (1994), J. Biol. Chem., 269, 15076-15084.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.4.19.1 | iodoacetamide | - |
Homo sapiens |  |
| 3.4.19.1 | N-acetyl-Met | - |
Homo sapiens | |
| 3.4.19.1 | p-nitrophenyl-N-propyl carbamate | potent active site-directed, pseudo-first-order kinetics | Homo sapiens | |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 3.4.19.1 | 0.01 | - |
2-naphthyl butyrate | - |
Homo sapiens | |
| 3.4.19.1 | 0.02 | - |
p-nitrophenylbutyrate | - |
Homo sapiens | |
| 3.4.19.1 | 0.06 | - |
4-nitrophenyl hexanoate | - |
Homo sapiens | |
| 3.4.19.1 | 0.07 | - |
p-nitrophenylvalerate | - |
Homo sapiens | |
| 3.4.19.1 | 0.16 | - |
p-nitrophenylpropionate | - |
Homo sapiens | |
| 3.4.19.1 | 0.63 | - |
4-nitrophenyl acetate | - |
Homo sapiens | |
| 3.4.19.1 | 1 | - |
butyryl thiocholine | - |
Homo sapiens | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.4.19.1 | Homo sapiens | - |
- |
- |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.19.1 | 2-naphthyl butyrate + H2O | - |
Homo sapiens | 2-naphthol + butanoate | - |
? | |
| 3.4.19.1 | 4-nitrophenyl acetate + H2O | - |
Homo sapiens | 4-nitrophenol + acetate | - |
? | |
| 3.4.19.1 | butyryl thiocholine + H2O | - |
Homo sapiens | ? | - |
? | |
| 3.4.19.1 | N-acetyl-Ala p-nitroanilide + H2O | - |
Homo sapiens | N-acetyl-Ala + p-nitroaniline | - |
? | |
| 3.4.19.1 | naphthyl butyrate + H2O | - |
Homo sapiens | naphthol + butyrate | - |
? | |
| 3.4.19.1 | p-nitrophenyl acetate + H2O | - |
Homo sapiens | 4-nitrophenol + acetate | - |
? | |
| 3.4.19.1 | p-nitrophenyl butyrate + H2O | - |
Homo sapiens | ? | - |
? | |
| 3.4.19.1 | p-nitrophenyl hexanoate + H2O | - |
Homo sapiens | p-nitrophenol + hexanoate | - |
? | |
| 3.4.19.1 | p-nitrophenyl propionate + H2O | - |
Homo sapiens | p-nitrophenol + propionate | - |
? | |
| 3.4.19.1 | p-nitrophenyl valerate + H2O | - |
Homo sapiens | p-nitrophenol + pentanoate | - |
? | |
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