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Literature summary extracted from

  • Spanner, S.; Ansell, G.B.
    Activation of glycerophosphocholine phosphodiesterase in rat forebrain by Ca2+ (1982), Biochem. J., 208, 845-850.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.4.2 EDTA complete inhibition at 0.005 mM Rattus sp.
3.1.4.2 EGTA
-
 Rattus sp.

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.1.4.2 plasma membrane significant levels in neurons and glia Rattus sp. 5886
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.1.4.2 Ca2+ activation at very low concentration Rattus sp.

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.4.2 sn-glycero 3-phosphorylcholine + H2O Rattus sp. cellular phosphatidylcholine catabolic pathway ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.4.2 Rattus sp.
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.4.2 forebrain
-
 Rattus sp.
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.1.4.2 0.005
-
-
 Rattus sp.

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.4.2 sn-glycero 3-phosphorylcholine + H2O
-
 Rattus sp. sn-glycerol 3-phosphate + choline
-
 ?
3.1.4.2 sn-glycero 3-phosphorylcholine + H2O cellular phosphatidylcholine catabolic pathway Rattus sp. ?
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.1.4.2 8 8.6
-
 Rattus sp.