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Literature summary extracted from

  • Spychala, J.; Madrid-Marina, V.; Fox, I.H.
    High Km soluble 5'-nucleotidase from human placenta. Properties and allosteric regulation by IMP and ATP (1988), J. Biol. Chem., 263, 18759-18765.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.1.3.5 2,3-diphosphoglycerate activation Homo sapiens
3.1.3.5 ATP activation Homo sapiens
3.1.3.5 dATP activation Homo sapiens

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.1.3.5 0.09
-
5'-IMP presence of 3 mM ATP Homo sapiens
3.1.3.5 0.13
-
5'-IMP presence of 3 mM ATP plus 4 mM phosphate Homo sapiens
3.1.3.5 0.33
-
5'-IMP
-
Homo sapiens
3.1.3.5 0.54
-
5'-IMP presence of 4 mM phosphate Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.1.3.5 cytoplasm
-
Homo sapiens 5737
-

Organism

EC Number Organism UniProt Comment Textmining
3.1.3.5 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.1.3.5
-
Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.3.5 placenta
-
Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.3.5 5'-dIMP + H2O i.e. 2'-deoxyinosine 5'-phosphate Homo sapiens deoxyinosine + phosphate
-
?
3.1.3.5 5'-dIMP + H2O 23% of the activity with 5'-IMP, cytoplasmic enzyme Homo sapiens deoxyinosine + phosphate
-
?
3.1.3.5 5'-GMP + H2O 85% of the activity with 5'-IMP, cytoplasmic enzyme Homo sapiens guanosine + phosphate
-
?
3.1.3.5 5'-IMP + H2O preferred substrate Homo sapiens inosine + phosphate
-
?
3.1.3.5 5'-UMP + H2O 14% of the activity with 5'-IMP, cytoplasmic enzyme Homo sapiens uridine + phosphate
-
?
3.1.3.5 5'-XMP + H2O 23% of the activity with 5'-IMP, cytoplasmic enzyme Homo sapiens xanthosine + phosphate
-
?