Literature summary extracted from

Pot, D.A.; Woodford, T.A.; Remboutsika, E.; Haun, R.S.; Dixon, J.E.
Cloning, bacterial expression, purification, and characterization of the cytoplasmic domain of rat LAR, a receptor-like protein tyrosine phosphatase (1991), J. Biol. Chem., 266, 19688-19696.

Cloned(Commentary)

EC Number	Cloned (Comment)	Organism
3.1.3.48	catalytic domain of receptor-like protein tyrosine phosphatase	Rattus norvegicus

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
3.1.3.48	iodoacetic acid	-	Rattus norvegicus
3.1.3.48	molybdate	-	Rattus norvegicus
3.1.3.48	N-ethylmaleimide	-	Rattus norvegicus
3.1.3.48	p-hydroxymercuribenzoate	-	Rattus norvegicus

KM Value [mM]

EC Number	KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
3.1.3.48	0.118	-	DRVpYIHPFHL	-	Rattus norvegicus
3.1.3.48	0.42	-	4-nitrophenyl phosphate	-	Rattus norvegicus

Localization

EC Number	Localization	Comment	Organism	GeneOntology No.	Textmining

Organism

EC Number	Organism	UniProt	Comment	Textmining
3.1.3.48	Rattus norvegicus	Q64604	-	-

Purification (Commentary)

EC Number	Purification (Comment)	Organism
3.1.3.48	catalytic domain	Rattus norvegicus

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining

Specific Activity [micromol/min/mg]

EC Number	Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
3.1.3.48	16.2	-	-	Rattus norvegicus

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
3.1.3.48	4-nitrophenyl phosphate + H2O	-	Rattus norvegicus	4-nitrophenol + phosphate	-	?
3.1.3.48	DRVpYIHPFHL + H2O	-	Rattus norvegicus	DRVYIHPFHL + phosphate	-	?

Turnover Number [1/s]

EC Number	Turnover Number Minimum [1/s]	Turnover Number Maximum [1/s]	Substrate	Comment	Organism	Structure
3.1.3.48	3.1	-	DRVpYIHPFHL	-	Rattus norvegicus
3.1.3.48	6.1	-	4-nitrophenyl phosphate	-	Rattus norvegicus

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)