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Literature summary extracted from
- Cloning, purification, and properties of a phosphotyrosine protein phosphatase from Streptomyces coelicolor A3(2) (1996), J. Bacteriol., 178, 136-142.
Cloned(Commentary)
| EC Number | Cloned (Comment) | Organism |
|---|---|---|
| 3.1.3.48 | expression in Escherichia coli | Streptomyces coelicolor |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.1.3.48 | dephostatin | - |
Streptomyces coelicolor |  |
| 3.1.3.48 | H3VO4 | - |
Streptomyces coelicolor | |
| 3.1.3.48 | iodoacetate | - |
Streptomyces coelicolor | |
| 3.1.3.48 | Phenylarsine oxide | - |
Streptomyces coelicolor | |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 3.1.3.48 | 0.00485 | - |
4-nitrophenyl phosphate | - |
Streptomyces coelicolor | |
| 3.1.3.48 | 2.7 | - |
phosphotyrosine | - |
Streptomyces coelicolor | |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 3.1.3.48 | 18258 | - |
x * 18258, calculation from the sequence of the fusion protein | Streptomyces coelicolor |
| 3.1.3.48 | 21000 | - |
x * 21000, SDS-PAGE | Streptomyces coelicolor |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.1.3.48 | Streptomyces coelicolor | - |
A3(2), GenBank U37580 | - |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 3.1.3.48 | - |
Streptomyces coelicolor |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.1.3.48 | 4-nitrophenyl phosphate + H2O | - |
Streptomyces coelicolor | 4-nitrophenol + phosphate | - |
? | |
| 3.1.3.48 | phosphotyrosine + H2O | - |
Streptomyces coelicolor | tyrosine + phosphate | - |
? | |
| 3.1.3.48 | TSTEPQpYQPGENL + H2O | - |
Streptomyces coelicolor | TSTEPQYQPGENL + phosphate | - |
? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 3.1.3.48 | ? | x * 18258, calculation from the sequence of the fusion protein | Streptomyces coelicolor |
| 3.1.3.48 | ? | x * 21000, SDS-PAGE | Streptomyces coelicolor |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 3.1.3.48 | PtpA | - |
Streptomyces coelicolor |
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