Literature summary extracted from

Feingold K.R.; Wiley M.H.; Moser A.H.; Lear S.R.; Siperstein M.D.
Activation of HMG-CoA reductase by microsomal phosphatase (1983), J. Lipid Res., 24, 290-296.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
3.1.3.47	fluoride	-	Rattus norvegicus
3.1.3.47	phosphate	-	Rattus norvegicus

Localization

EC Number	Localization	Comment	Organism	GeneOntology No.	Textmining
3.1.3.47	cytosol	-	Rattus norvegicus	5829	-
3.1.3.47	microsome	-	Rattus norvegicus	-	-
3.1.3.47	rough endoplasmic reticulum	-	Rattus norvegicus	5791	-
3.1.3.47	smooth endoplasmic reticulum	-	Rattus norvegicus	5790	-

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
3.1.3.47	[hydroxymethylglutaryl-CoA reductase (NADPH)] phosphate + H2O	Rattus norvegicus	-	?	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
3.1.3.47	Rattus norvegicus	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
3.1.3.47	liver	-	Rattus norvegicus	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
3.1.3.47	[hydroxymethylglutaryl-CoA reductase (NADPH)] phosphate + H2O	-	Rattus norvegicus	[hydroxymethylglutaryl-CoA reductase (NADPH)] + phosphate	-	?
3.1.3.47	[hydroxymethylglutaryl-CoA reductase (NADPH)] phosphate + H2O	-	Rattus norvegicus	?	-	?

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Release 2023.1 (January 2023)